Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Does erythropoietin improve preterm babies development?

Posted on 15 March 2016 by Keith Barrington

Ohls RK, et al. Preschool Assessment of Preterm Infants Treated With Darbepoetin and Erythropoietin. Pediatrics. 2016;137(3):1-9. Robin Ohls has been working on Erythropoietin, and its longer acting analogue darbepoietin, for many years now. As well as demonstrating that it stimulates … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

Early low dose systemic hydrocortisone to prevent death or chronic lung disease? Hold on a bit.

Posted on 11 March 2016 by Keith Barrington

An important high quality trial has just been published, it has taken me a bit longer than usual to process the new info. Among other reasons a nice review was posted on the “other neonatal blog“, but I wanted to … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 2 Comments

Lacuna trial now in print

Posted on 10 March 2016 by Keith Barrington

Now available on-line the pilot trial of lactoferrin prophylaxis that I performed at Sainte Justine. (Barrington KJ, Assaad M-A, Janvier A. The Lacuna Trial: a double-blind randomized controlled pilot trial of lactoferrin supplementation in the very preterm infant. J Perinatol. … Continue reading →

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Videolaryngoscopy to teach intubation

Posted on 10 March 2016 by Keith Barrington

Two recent randomized trials, one from our group, and another one from Melbourne have evaluate the role of the videolaryngoscope (VL) in teaching trainees in neonatology to perform endotracheal intubations. The two trials are structured differently and tell us different … Continue reading →

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Steroids directly in the lungs? Version 2

Posted on 24 February 2016 by Keith Barrington

A couple of weeks ago I discussed a new multicenter RCT which examined the effects of multiple repeated doses of steroids, given by inhalation starting on the first day of life, and continuing, at least until the infants reached 14 … Continue reading →

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Still more doubts about BOOSTing saturations?

Posted on 22 February 2016 by Keith Barrington

I won’t make a point-by-point response to Reese’s comments, mostly because I agree with most of them! Oxygen is toxic. Minimizing oxygen toxicity is a vitally important issue. Alarm fatigue is a major problem. In our NICU we performed an … Continue reading →

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All oscillators are equal, but some oscillators are more equal than others

Posted on 22 February 2016 by Keith Barrington

My readers are a highly educated bunch and I am sure that the anglophones among you will recognize that title as a bastardized quotation from “Animal Farm”. Not my favorite of George Orwell, a bit too obvious as an analogy … Continue reading →

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More Doubts about BOOSTing saturations?

Posted on 22 February 2016 by Keith Barrington

As I just mentioned I received another thoughtful comment from Reese Clark, which I reproduce in its entirety below: “After re-reading my post and at the risk of being a bit redundant with what Dr Barrington has already carefully presented … Continue reading →

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Doubts about BOOSTING saturations?

Posted on 22 February 2016 by Keith Barrington

I received a very thoughtful comment from Reese Clark, who many of you will know as a leader in neonatology whose many years of experience and important scientific contributions to neonatology make him someone worth listening to. He has doubts … Continue reading →

Posted in Neonatal Research | Tagged , , , | 3 Comments

Do Clinical Guidelines make a difference?

Posted on 17 February 2016 by Keith Barrington

The question in the title is hard to answer, without a randomized controlled trial of some kind where the guidelines are followed in one group, and not in another. The whole point of most guidelines, though, is to put the … Continue reading →

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