Tag Archives: oxygen therapy

I want a Guarantee.

Enomoto M, et al. Effect of Volume Guarantee in Preterm Infants on High-Frequency Oscillatory Ventilation: A Pilot Study. American journal of perinatology. 2016(EFirst). One of the things that really bugs me (and there are many, as my gentle readers will … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment

Still more doubts about BOOSTing saturations?

I won’t make a point-by-point response to Reese’s comments, mostly because I agree with most of them! Oxygen is toxic. Minimizing oxygen toxicity is a vitally important issue. Alarm fatigue is a major problem. In our NICU we performed an … Continue reading

Posted in Neonatal Research | Tagged , , , , | 1 Comment

More Doubts about BOOSTing saturations?

As I just mentioned I received another thoughtful comment from Reese Clark, which I reproduce in its entirety below: “After re-reading my post and at the risk of being a bit redundant with what Dr Barrington has already carefully presented … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

BOOST-II long term outcomes

The long-running epic of the oxygen saturation targeting trials is nearing completion. This publication of the joint results of the Australia and UK trials now includes the primary outcome for the trials, the combined rate of death or “disability”. Australia … Continue reading

Posted in Neonatal Research | Tagged , , , | 1 Comment

Treating pneumothoraces? Either a tube or leave them alone.

I never understood why it was recommended to give 100% oxygen to treat a pneumothorax. I think the idea was that the gas in the pneumothorax could be replaced by oxygen which would then be reabsorbed more quickly if we … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment

Resuscitating preterm infants: how many O’s

Very often in neonatology (and in life) we have to make a decision based on inadequate data. For example, when resuscitating a very preterm baby you have to decide where to set the starting FiO2, even if there are no … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Oxygen, transfusions, and NEC

What causes NEC! The answer is ‘who knows?’, or perhaps a better one would be ‘its complicated…’ You probably need an immature gut, gut mucosal injury, inflammation and cytokine release, and an abnormal microbiome, all of which probably interact in … Continue reading

Posted in Neonatal Research | Tagged , , , , , | Leave a comment