Tag Archives: oxygen therapy

Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM

The NeoProm primary publication is the result of a prolonged gestation; I remember meetings over 15 years ago when Cynthia Cole from Boston was suggesting the idea, and although she was not, I think, finally an author on any of … Continue reading

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PAS 2018: the wrap-up.

A general comment about these PAS 2018 blog posts. I think we should be very careful about changing practice based on an abstract. We should respect peer review, with all its limitations, and we should always consider new research in … Continue reading

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Too much oxygen is bad for adults too!

The systematic review of the neonatal oxygen saturation targeting trials Askie LM, et al. Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants. Cochrane database of systematic reviews (Online). 2017;4:Cd011190. confirmed the increase … Continue reading

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I want a Guarantee.

Enomoto M, et al. Effect of Volume Guarantee in Preterm Infants on High-Frequency Oscillatory Ventilation: A Pilot Study. American journal of perinatology. 2016(EFirst). One of the things that really bugs me (and there are many, as my gentle readers will … Continue reading

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Still more doubts about BOOSTing saturations?

I won’t make a point-by-point response to Reese’s comments, mostly because I agree with most of them! Oxygen is toxic. Minimizing oxygen toxicity is a vitally important issue. Alarm fatigue is a major problem. In our NICU we performed an … Continue reading

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More Doubts about BOOSTing saturations?

As I just mentioned I received another thoughtful comment from Reese Clark, which I reproduce in its entirety below: “After re-reading my post and at the risk of being a bit redundant with what Dr Barrington has already carefully presented … Continue reading

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BOOST-II long term outcomes

The long-running epic of the oxygen saturation targeting trials is nearing completion. This publication of the joint results of the Australia and UK trials now includes the primary outcome for the trials, the combined rate of death or “disability”. Australia … Continue reading

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