Monthly Archives: May 2014

New Lactoferrin Data

Two new articles addressing effects of lactoferrin. Both used bovine lactoferrin (bLF), one was in humans, the other in piglets. In case you haven’t been following closely, lactoferrin is an iron transport protein that has multiple anti-infective properties, against bacteria, … Continue reading

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Filling Buckets

The title of this post is the title of a wonderful new article in JAMA; an article describing 3 patient encounters by 2 physicians at different stages of their career and a medical student. Read it if you have access, and if you want to … Continue reading

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Low Cardiac Output after PDA ligation

Some babies after PDA ligation develop a low cardiac output, Patrick McNamara and his colleagues have defined that as being less than 200 mL/kg/min left ventricular output. This cohort study of 30 infants post-ligation, by Afif El-Khuffash and colleagues at … Continue reading

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Neonatal Updates

Dardas M, Gill SR, Grier A, Pryhuber GS, Gill AL, Lee Y-H, et al. The Impact of Postnatal Antibiotics on the Preterm Intestinal Microbiome. Pediatr Res. 2014. It will be no surprise to readers of this blog that antibiotics are … Continue reading

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All trials reported, all results available

The ‘All trials’ campaign is picking up steam, a new video is embedded below. I think the inclusion of a patient volunteer was a great idea, the altruistic aspect of consent for clinical trials, and the betrayal of that altruism … Continue reading

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Probiotics in preterm infants: not just for NEC prevention any more

A new RCT in more mature preterm infants 32 to 37 weeks compared the incidence of viral respiratory infections during the first year of life between infants who received prebiotics (galacto-oligosaccharide and polydextrose) probiotics (lactobacillus rhamnosus) or placebo between the … Continue reading

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Hero: Not just for infections any more

Sullivan BA, Grice SM, Lake DE, Moorman JR, Fairchild KD. Infection and Other Clinical Correlates of Abnormal Heart Rate Characteristics in Preterm Infants. The Journal of pediatrics. 2014. Monitoring for abnormal heart rate characteristics has previously been shown in a … Continue reading

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