Tag Archives: mortality

What is happening for the most preterm deliveries.The Completed Week Heuristic.

Posted on 17 June 2022 by Keith Barrington

There are several recent publications about deliveries at 22 to 25 weeks gestation, evaluating the frequency of intensive care support of the babies, factors associated with support, and survival. The California Perinatal Quality Care Collaborative reports the proportion of “active … Continue reading →

Posted in Neonatal Research | Tagged , | 1 Comment

Was OPTIMIST too optimistic?

Posted on 5 January 2022 by Keith Barrington

One of the trials we have been waiting for has just been published Dargaville PA, et al. Effect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A … Continue reading →

Posted in Neonatal Research | Tagged , , | 4 Comments

Intestinal perforation in the very preterm, what causes it, and what to do about it.

Posted on 24 September 2021 by Keith Barrington

There are 2 main causes of intestinal perforation in the very preterm, Necrotising Enterocolitis and Spontaneous Perforation. NEC, as I have previously discussed, may be a convenient name for a few different conditions which present in a similar fashion. In … Continue reading →

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Extreme preterm survival and outcomes

Posted on 16 September 2021 by Keith Barrington

There are frequently publications about the outcomes of extreme preterm infants; as a community I think we should be proud of our investment in outcome research. Indeed, neonatologists invented the entire field of outcomes research (Barrington KJ, Saigal S. Long-term … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment

The ACOG patient information page; what should it say about 22, 23, 24 weekers?

Posted on 16 April 2021 by Keith Barrington

I mentioned not so long ago that the web page of the US Obstetricians professional association has information for prospective parents of babies of less than 25 weeks gestation that is… questionable. They state, for example, the following : Medical … Continue reading →

Posted in Neonatal Research | Tagged , | 7 Comments

Outcomes of infants born at 22 weeks gestation; attitudes are the best predictor of survival

Posted on 10 August 2020 by Keith Barrington

Among the most immature infants, mortality and morbidity are common even if they receive active neonatal intensive care, a new systematic review has attempted to find out how common. Backes CH, et al. Proactive Neonatal Treatment at 22 Weeks of … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

What to do about early postnatal steroids?

Posted on 3 March 2020 by Keith Barrington

Steroid metabolism in the very immature infant is… immature. Adrenal function is still developing in the fetus between 20 and 26 weeks, and a source of precursors from the placenta is important, but obviously disappears at delivery. Very preterm babies … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 2 Comments

The jaundiced eye of the beholder

Posted on 3 February 2020 by Keith Barrington

Well, this is disappointing, the amazing results from Iowa regarding the outcomes of infants born at 22 and at 23 weeks gestation have now been published in the February print edition of the Journal of Pediatrics. What is disappointing about … Continue reading →

Posted in Neonatal Research | Tagged | 3 Comments

Giving bad news as it happens

Posted on 30 January 2020 by Keith Barrington

A new publication from my great group at Sainte Justine. Lizotte MH, et al. Techniques to Communicate Better With Parents During End-of-Life Scenarios in Neonatology. Pediatrics. 2020:e20191925. We have already published about what residents think about being part of a … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Erythropoietin for brain protection in the very preterm? Not worth Penuts.

Posted on 17 January 2020 by Keith Barrington

That isn’t a mis-spelling, just a bad attempt to play with the acronym for a good trial; the PENUT trial, just published in the (FP)NEJM. (Juul SE, et al. A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants. N … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 2 Comments