Tag Archives: mortality

Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM

The NeoProm primary publication is the result of a prolonged gestation; I remember meetings over 15 years ago when Cynthia Cole from Boston was suggesting the idea, and although she was not, I think, finally an author on any of … Continue reading

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PAS 2108 No4: you little SCAMP!

In the part of England where I was born and spent the early years of my life, and where my parents are from, the Manchester region, ‘scamp’ was a sort of affectionate term for a young child who had done … Continue reading

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PAS 2018 No3: Should we TOLERATE the PDA?

This was another large multicenter trial, designed to determine if routine attempts to close a moderate to large PDA at the end of the first postnatal week decreases the duration of patency, and the incidence of the combined outcome “need … Continue reading

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PAS 2018 No1: SAIL away (and another mention by a science journalist).

For some reason there is a small epidemic (n=2, that’s a pico-epidemic) of articles about probiotics and necrotising enterocolitis this year in the mainstream press. I was interviewed, and I am mentioned again, in this article on the NOVA “next” … Continue reading

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Regular universal antibiotics to reduce infant mortality?

This (Keenan JD, et al. Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa. The New England journal of medicine. 2018;378(17):1583-92 Open Access) is a new multicenter cluster randomized trial of giving all infants in a community regular azithromycin. If that … Continue reading

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Too much oxygen is bad for adults too!

The systematic review of the neonatal oxygen saturation targeting trials Askie LM, et al. Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants. Cochrane database of systematic reviews (Online). 2017;4:Cd011190. confirmed the increase … Continue reading

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New Published Letter, a response to the ‘number needed to suffer’.

The new issue of Acta Paediatrica (Februray 2018) includes a letter I wrote in response to a commentary written by a paediatric anaesthetist, Dr Lönnqvist. If you receive an email with a description of the contents of each issue, as … Continue reading

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