Tag Archives: long term outcomes

Antenatal steroids : good, bad, or both?

Posted on 27 May 2020 by

Antenatal steroids prior to very preterm birth save lives. Antenatal steroids prior to planned late preterm delivery reduce respiratory distress and increase hypoglycaemia. Might there be other long-term effects on brain structure? There are now some animal models which suggest … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

Linezolid seems safe for preterms, probably

Posted on 5 March 2020 by

A few years ago we started having difficulty clearing Coagulase-Negative Staphylococcal (CoNS) sepsis from the blood cultures of some babies in our NICU, children with CoNS also seemed to be sicker, and to more often have thrombocytopenia. It was at … Continue reading →

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What is hypoglycaemia? Part 3. Part of the answer!

Posted on 14 February 2020 by

The only way that we can find the answer to the question of what threshold blood sugar we should use to treat babies with low blood sugars is a prospective RCT, and Behold! Look! Lo! How say you? (van Kempen … Continue reading →

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What is hypoglycemia? part 2

Posted on 13 February 2020 by

The new statement from the CPS, and many others, don’t discuss which measurement that we are really interested in, is it blood glucose, or plasma glucose? The different data sources are discussed as if they were all measuring the same … Continue reading →

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What is hypoglycaemia? Part 1.

Posted on 11 February 2020 by

The Canadian Pediatric Society has just published new guidance for screening and treatment of infants at risk for neonatal hypoglycaemia. The older statement needed to be revised, in particular to include the use of oral glucose gel as an option, … Continue reading →

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Erythropoietin for brain protection in the very preterm? Not worth Penuts.

Posted on 17 January 2020 by

That isn’t a mis-spelling, just a bad attempt to play with the acronym for a good trial; the PENUT trial, just published in the (FP)NEJM. (Juul SE, et al. A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants. N … Continue reading →

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Not futile any more; survival and long term outcomes at 22 weeks.

Posted on 15 October 2019 by

Imagine, if you will, that you work at a breast cancer center with moderately good results, but you have decided, as a group, to not offer therapy to women with stage 4- triple negative lesions. Survival is so low, you … Continue reading →

Posted in Neonatal Research | Tagged , , | 11 Comments

Growing bigger, or growing better?

Posted on 6 December 2018 by

Babies with postnatal growth failure in the NICU do worse in the long term. This is a statistical association known for a long time. We also know that increasing nutritional intake, in calories and protein can prevent the relative weight … Continue reading →

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Active intervention at 22 weeks gestation, is it futile?

Posted on 29 October 2018 by

In order to respond to the question posed in the title we need first to agree on what “futile” means. It could mean “it never works” or, “it can work but the ultimate result is so bad that it isn’t … Continue reading →

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All that pneumatoses is not NEC

Posted on 17 October 2018 by

OK, I know pneumatose is not a verb, but I thought it was a cute title. What is NEC, anyway? Necrotizing Enterocolitis, of course, you might reply. But it’s not as simple as that. The very preterm baby who deteriorates … Continue reading →

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