Tag Archives: long term outcomes

“Death or NDI” does it matter… to anybody?

Posted on 30 May 2023 by Keith Barrington

Despite the evidence that “NDI” is of little interest to parents, we continue to focus on it in outcome studies, and even equate it with death. Unfortunately, this new study, using the substantial resources of the NICHD NRN and their … Continue reading →

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What outcomes matter to parents?

Posted on 25 May 2023 by Keith Barrington

Following on from my 2 recent posts, a new publication from the CHILD-BRIGHT network in Canada, (Synnes A, et al. Redefining Neurodevelopmental Impairment: Perspectives of Very Preterm Birth Stakeholders. Children. 2023;10(5) Open Access). CHILD-BRIGHT being a slightly tortuous acronym derived … Continue reading →

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Shifting the uncertainty a little further: severe early ultrasound abnormalities in the preterm. part 2

Posted on 18 May 2023 by Keith Barrington

In this post, I continue to discuss some of the issues raised in our recent article: Chevallier M, Barrington KJ et al. Decision-making for extremely preterm infants with severe hemorrhages on head ultrasound: Science, values, and communication skills. Semin Fetal … Continue reading →

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Shifting the uncertainty: early head ultrasound abnormalities, and counselling parents. Part 1

Posted on 17 May 2023 by Keith Barrington

Routine early head ultrasound is the de facto standard of care in preterm infants. Recent statements from learned societies usually recommend head ultrasound at around 7 days of age, and many centres do them earlier than that. Older statements suggested … Continue reading →

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PAS 2023, some supplemental selected stuff

Posted on 8 May 2023 by Keith Barrington

As usual, the annual meeting of PAS had too many things going on simultaneously to be able to get to all the interesting looking neonatal research. But here are a few things, that were of interest to me, and which … Continue reading →

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Imaging after therapeutic hypothermia: when to do the MRI (if at all)

Posted on 19 April 2023 by Keith Barrington

I had thought it was well settled that imaging soon after rewarming was as good for predicting outcomes in HIE as later imaging, but it seems that the timing, and the methodology are still uncertain. Tabacaru C, et al. Diffusion … Continue reading →

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Pulmonary outcomes in the preterm: beyond BPD

Posted on 17 April 2023 by Keith Barrington

A long break since my last post. I have had a couple of trips, to Arizona and to Australia, and more recently to Washington DC. With each conference I now try, if I can, to take an extra few days … Continue reading →

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How much protein should we provide to the preterm in the first days of life?

Posted on 11 November 2022 by Keith Barrington

Extremely preterm infants become catabolic rapidly after birth, with the sudden interruption of their trans-placental nutrient supply to the fetus, who becomes a baby that has tiny stores of fat or glycogen. We progressed in neonatology from starving preterm babies … Continue reading →

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What dose of caffeine to use?

Posted on 9 September 2022 by Keith Barrington

The dose of caffeine that we used for the CAP trial was the dose that was being widely used at the time. It seemed to be a safe dose, that did not require serum concentration surveillance, but was not based … Continue reading →

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Toxicity of antenatal steroids on the developing brain.

Posted on 4 September 2022 by Keith Barrington

A new study from Finland this time, raises similar concerns to those from a Canadian study. (Raikkonen K, et al. Associations Between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children. JAMA Netw Open. 2022;5(8):e2228518). It is … Continue reading →

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