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Tag Archives: long term outcomes
World NEC awareness day, part 2
As well as all the high tech mechanistic studies in NEC, such as those that I just posted about, sometimes we need to take a step back and ask some very basic questions. What is the current natural history of … Continue reading
Long term impacts of antenatal steroids
To return to a concern expressed in a recent blog, there are animal models and some observational data that suggest that antenatal steroids (ANS) could have a negative effect on cerebral development, at least with the doses used currently. Among … Continue reading
Posted in Neonatal Research
Tagged antenatal steroids, long term outcomes, Systematic Reviews
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Antenatal steroids prior to late preterm delivery; still many questions, but a major shift in practice.
It can sometimes take years for major advances in medicine, based on clear evidence of improved outcomes, to lead to shifts in practice. One example is the initial demonstration by Liggins and Howie that antenatal steroids (ANS) improved survival of … Continue reading
Preterm babies, PLEASE don’t smoke!
One of the most addictive and harmful drugs of all is perfectly legal. Tobacco, and the nicotine it contains, are subject to prohibition for adults nowhere in the world, despite millions of deaths, prolonged severe disability, and being probably as … Continue reading
We need to rethink neonatal hypoglycaemia
A great deal of time and effort is expended to detect and treat low blood sugars in the newborn. Studies to determine risk factors, monitoring schedules, and treatment strategies have taken a great deal of effort, and implementing the recommended … Continue reading
Steroids to improve pulmonary outcomes in preterm infants.
When we consider using steroids in a preterm infant, ventilator dependent, with evolving lung disease, what outcomes are we most interested in? Survival, surely, is the first outcome that we want to improve, and secondly long-term pulmonary health. The adverse … Continue reading
Posted in Neonatal Research
Tagged BPD, long term outcomes, Randomized Controlled Trials
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Dexmedetomidine: new wonder drug or next neonatal disaster?
In many units, including my own, dexmedetomidine (DXM) has been creeping into use. Initially, we noticed in some full term babies who returned from the operating room, the medication appeared in the anaesthesia record, then when infants returned occasionally with … Continue reading
What do we tell families at 22 weeks?
When we counsel families about the potential outcomes for infants born profoundly preterm, I think we would all agree that we should be honest, transparent and truthful. Which includes, I would suggest, truthfulness about our own local results, as well … Continue reading
Speak French to your babies (or Chinese) in the NICU
This is a fascinating study from Columbus Ohio in mildly preterm babies when they reached term. (Richard C, et al. Randomized Trial to Increase Speech Sound Differentiation in Infants Born Preterm. J Pediatr. 2021) We know that prematurity and NICU … Continue reading
Survival and longer term outcomes for the extremely preterm. The NICHD network results.
In addition to the short term results that I just posted about, the publication from the NICHD NRN describes the longer term outcomes of the babies of 22 to 26 weeks GA born between 2013-2016 who completed their 2 year … Continue reading
Neonatal Research 