Tag Archives: long term outcomes

New Published Letter, a response to the ‘number needed to suffer’.

Posted on 2 February 2018 by

The new issue of Acta Paediatrica (Februray 2018) includes a letter I wrote in response to a commentary written by a paediatric anaesthetist, Dr Lönnqvist. If you receive an email with a description of the contents of each issue, as … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Inhaled Steroids to Prevent BPD? Think again… again!

Posted on 16 January 2018 by

The NEUROSIS trial that I discussed in my previous post has, among other published trials, most in common with the trial by Nakamura published in 2016. Nakamura T, et al. Early inhaled steroid use in extremely low birthweight infants: a … Continue reading →

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Inhaled steroids to prevent BPD? Think again…

Posted on 15 January 2018 by

The NEUROSIS trial was a high quality trial of inhaled budesonide started before 12 hours in extremely preterm infants (23 to <28 weeks gestation) receiving positive pressure respiratory support. The primary outcome of the trial was survival without needing oxygen … Continue reading →

Posted in Neonatal Research | Tagged , , , | Leave a comment

Time to abandon the Papile classification? (part 2)

Posted on 7 December 2017 by

As I mentioned in the last post, the initial report of outcomes by Bassan and others showed that the infants with severity score 0, (unilateral haemorrhage without midline shift affecting one zone) had reasonably good outcomes, 7 of 8 had … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments

The end of the Papile classification? (part 1)

Posted on 28 November 2017 by

In 1978 Lu-Ann Papile published a landmark article detailing the incidence of intraventricular hemorrhage (IVH) in 46 VLBW preterm infants using CT scanning, describing the differing extent of hemorrhage that may be seen, and developing a grading system (there are … Continue reading →

Posted in Neonatal Research | Tagged , , | 3 Comments

Recent publications

Posted on 16 November 2017 by

Even though the blog has been quiet recently, other academic output has continued… In the NICU we are often faced with babies with late- or early- onset sepsis. The worst cases develop shock, which carries a significant mortality; they may … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments

What to do with mild encephalopathy?

Posted on 13 November 2017 by

Therapeutic hypothermia improves the chances of babies with moderate or severe hypothermia of surviving without serious disability; referrals for evaluation for therapeutic hypothermia have exploded in our center, and many others, now that this advance is widely acknowledged. Many of … Continue reading →

Posted in Neonatal Research | Tagged , , | 6 Comments