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Author Archives: Keith Barrington
What is happening for the most preterm deliveries.The Completed Week Heuristic.
There are several recent publications about deliveries at 22 to 25 weeks gestation, evaluating the frequency of intensive care support of the babies, factors associated with support, and survival. The California Perinatal Quality Care Collaborative reports the proportion of “active … Continue reading
The list of shame, and the continued shame of the Journal “Pain”
Randomized controlled trials of pain control measures prior to planned painful procedures that have an untreated control group are unethical. I would have thought in 2022 that statement was about as uncontroversial as a statement about ethics could be, nevertheless … Continue reading
Posted in Neonatal Research
Tagged analge, pain, Randomized Controlled Trials, Systematic Reviews
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Bronchopulmonary Dysplasia; does it matter?
I just published a “different view” article addressing the question in the title, with a group of expert collaborators, Mai Luu who is our follow up doc in Montreal, and helps to run the Canadian Neonatal Follow-Up Network (CNFUN), Paige … Continue reading
Preventing desaturation during intubation. Shine on, you crazy….
Recommendations for older children and adults during endotracheal intubation frequently include the use of free flow oxygen, indeed when I was a fellow with Neil Finer we routinely provided additional free flow oxygen from a catheter placed near the nose, … Continue reading
World NEC awareness day, part 2
As well as all the high tech mechanistic studies in NEC, such as those that I just posted about, sometimes we need to take a step back and ask some very basic questions. What is the current natural history of … Continue reading
World NEC awareness day.
As we approach world NEC awareness day (May 17th) I thought I’d do a quick PubMed search to see if I’ve missed anything recently, so I started typing “necrotizing” in the search bar, which immediately suggested “necrotizing enterocolitis” as one … Continue reading
Posted in Neonatal Research
Tagged microbiome, Necrotising Enterocolitis, Prebiotics, Probiotics
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Maternal breast milk is risky too
Human breast milk, when freshly expressed, contains all sorts of goodies, to use the technical scientific term. Many of which are adversely affected by standard pasteurisation (called Holder pasteurisation, which is very similar to what Louis Pasteur himself invented in … Continue reading
AAP guidance on probiotics. As wrong-headed as a head can be wrong.
The AAP issued guidance on probiotic use in the preterm infant last year in the form of what they call a “clinical report”, which I didn’t comment on at the time, I thought it might be a bit redundant as … Continue reading
Automated oxygen control, what’s taking so long?
A long long time ago, in a galaxy… actually quite near here, the idea of servo control of inspired oxygen was already in the air. At the time I first heard about it, the idea was to control FiO2 based … Continue reading
Not neonatology: missed all my friends at PAS, but be back next year, I hope.
I was disappointed to not be able to go to PAS this year, mostly because I am privileged to have a circle of former trainees, colleagues and friends from around the world who are all involved in trying to improve … Continue reading
Posted in Neonatal Research
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Neonatal Research 