Author Archives: keithbarrington

About keithbarrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Are these data relevant to my practice?

Posted on 21 June 2019

A couple of recent published trials have made me wonder about that question, and how to assess if an impact suggested by the results of a trial might be relevant to how I practice, and would likely be reproduced if … Continue reading →

Posted in Neonatal Research | 1 Comment

Pulse Oximetry screening; a bizarre decision in the UK.

Posted on 20 June 2019

Universal pulse oximetry screening for critical congenital heart disease is a simple cheap addition to universal hearing and metabolic screening with undeniable benefits. Infants with undiagnosed life threatening congenital heart disease can be detected prior to closure of the ductus … Continue reading →

Posted in Neonatal Research | Tagged , | 1 Comment

Gastric acid is good for your bones.

Posted on 17 June 2019

We’ve known for a while now that suppressing gastric acid production in preterm infants increases Necrotising Enterocolitis and also systemic sepsis. Presumably this is because the intestinal microbiome is deranged by allowing the survival of pathogens as they pass through … Continue reading →

Posted in Neonatal Research | Tagged , | 1 Comment

What respiratory outcomes are important?

Posted on 31 May 2019

When bronchopulmonary dysplasia was first described by Northway in 1967 he didn’t try to produce a definition, his paper was a description of a small number of preterm survivors of high oxygen and positive pressure ventilation. He noted some years … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

High-flow in non-tertiary neonatal units: Hunting for answers. #EBNEO

Posted on 27 May 2019

I think Brett Manley is going for the record as the person with the highest proportion of his publications in the FPNEJM, he now has 3, with 2 of them as first author. This is the HUNTER trial where babies … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

Research Outcomes in Neonatology : must do better.

Posted on 24 May 2019

When planning a research project with neonatal patients the first question should be, what am I investigating? The PICO outline : standing for Patients, Intervention, Controls (or comparison) and Outcome, is a standardized way of asking the simple question. If … Continue reading →

Posted in Neonatal Research | Tagged , | 3 Comments

Just do it! Who should go home on oxygen?

Posted on 15 May 2019

A new guideline from the ATS has been published, which gives guidelines for home oxygen therapy for children, one large group of which is, of course, babies with bronchopulmonmary dysplasia. Hayes D, Jr., et al. Home Oxygen Therapy for Children. … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments