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Author Archives: keithbarrington
Dr William Meadow 1948-2019
A sad way to fire up the blog after a long summer break. My good friend and colleague, Bill Meadow, died a few days ago. I first got to know Bill when I was junior faculty in Edmonton. At that … Continue reading
Posted in Neonatal Research
1 Comment
Are these data relevant to my practice?
A couple of recent published trials have made me wonder about that question, and how to assess if an impact suggested by the results of a trial might be relevant to how I practice, and would likely be reproduced if … Continue reading
Posted in Neonatal Research
1 Comment
Pulse Oximetry screening; a bizarre decision in the UK.
Universal pulse oximetry screening for critical congenital heart disease is a simple cheap addition to universal hearing and metabolic screening with undeniable benefits. Infants with undiagnosed life threatening congenital heart disease can be detected prior to closure of the ductus … Continue reading
Gastric acid is good for your bones.
We’ve known for a while now that suppressing gastric acid production in preterm infants increases Necrotising Enterocolitis and also systemic sepsis. Presumably this is because the intestinal microbiome is deranged by allowing the survival of pathogens as they pass through … Continue reading
What respiratory outcomes are important?
When bronchopulmonary dysplasia was first described by Northway in 1967 he didn’t try to produce a definition, his paper was a description of a small number of preterm survivors of high oxygen and positive pressure ventilation. He noted some years … Continue reading
Posted in Neonatal Research
Tagged BPD, Randomized Controlled Trials, Research Design, Systematic Reviews
1 Comment
High-flow in non-tertiary neonatal units: Hunting for answers. #EBNEO
I think Brett Manley is going for the record as the person with the highest proportion of his publications in the FPNEJM, he now has 3, with 2 of them as first author. This is the HUNTER trial where babies … Continue reading
Posted in Neonatal Research
Tagged CPAP, endotracheal intubation, High-Flow cannula, Randomized Controlled Trials
1 Comment
Research Outcomes in Neonatology : must do better.
When planning a research project with neonatal patients the first question should be, what am I investigating? The PICO outline : standing for Patients, Intervention, Controls (or comparison) and Outcome, is a standardized way of asking the simple question. If … Continue reading
