Author Archives: keithbarrington

About keithbarrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Happy New Review no. 2; Inhaled NO in the full term infant

We have also updated the Cochrane review of inhaled NO in the term infant. (Barrington KJ, Finer N, Pennaforte T, Altit G. Nitric oxide for respiratory failure in infants born at or near term. Cochrane database of systematic reviews (Online). … Continue reading

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Happy New Year! And Happy Reading; an update of the Cochrane review: nitric oxide in the preterm

A major revision of the Cochrane review of inhaled nitric oxide gas in the preterm infant is now available. (Barrington KJ, Finer N, Pennaforte T. Inhaled nitric oxide for respiratory failure in preterm infants. Cochrane database of systematic reviews (Online). … Continue reading

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You can’t diagnose reflux with a laryngoscope!

I have seen in several places, and heard other neonatologists from elsewhere make snide comments about, a very high frequency of the diagnosis of serious reflux by ENT surgeons. Almost every time a consultation is requested, for almost any indication, … Continue reading

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Venous catheters and thrombosis, risk factors, consequences and treatment.

We had a journal club for the fellows lately, everyone had to find an article about venous thrombosis and association with central catheters. We chose the topic because seem to have many more thromboses than in the past, whether that … Continue reading

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Inhaled steroids for BPD?

In a recent post I promoted a new Barrington rule for meta-analysis (it probably already existed somewhere but I am claiming priority anyway, it’s a “post-truth” kind of thing). The rule was that in a systematic review you shouldn’t pool … Continue reading

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Toxicity of reflux medications in infancy

Before I leave the topic for at least a few days, I thought I would discuss data about the toxicity of reflux medications in older children. Most of my ‘toxic placebo’ comments have been about studies in preterm infants, and … Continue reading

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Anti-reflux medications in preterm infants; a whole cornucopia of toxic placebos.

I have written frequently about this on my blog in the past, and even written a book chapter about the subject (in the book titled “Nutrition for the Preterm Neonate” edited by Sanjay Patole). I recently mentioned the subject in my … Continue reading

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