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Recent Posts
- Two amazing trials, at the opposite ends of the spectrum. What a weird world.
- What do you think are meaningful long term outcomes for preterm infants? Give your opinion!
- Which is worse; death or a low Bayley score? Comparing composite outcomes between groups, taking into account clinical priorities.
- Renal Function in the very immature preterm, what is a “normal” creatinine
- Longer-term outcomes: what should we measure? part 2
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Tag Archives: Ethics
Two amazing trials, at the opposite ends of the spectrum. What a weird world.
In the most recent NEJM two trials impacting newborn/paediatric care. One including 3,211 preterm infants, which shows that a very simple intervention could save, I estimate, tens of thousands of lives each year at almost no cost; the other with … Continue reading
Do estimates of survival change decisions made?
Kidszun A, et al. Effect of Neonatal Outcome Estimates on Decision-Making Preferences of Mothers Facing Preterm Birth: A Randomized Clinical Trial. JAMA Pediatr. 2020. This is a short report of an interesting idea, published as a research letter. The authors … Continue reading
Giving bad news as it happens
A new publication from my great group at Sainte Justine. Lizotte MH, et al. Techniques to Communicate Better With Parents During End-of-Life Scenarios in Neonatology. Pediatrics. 2020:e20191925. We have already published about what residents think about being part of a … Continue reading
Gene therapy for SMA; who will win the lottery?
There are few things more disgusting than the obscene actions of drug companies that profit off the distress of dying babies and their families. You might think that the price of a drug would be based on development and production … Continue reading
Therapeutic Hypothermia post cardiac arrest
This is a bit off-topic for this blog, but many of you will know that cooling is now used for many other patients than just our full-term asphyxias. Adults who remain with depressed levels of consciousness after resuscitation from a … Continue reading
Not futile any more; survival and long term outcomes at 22 weeks.
Imagine, if you will, that you work at a breast cancer center with moderately good results, but you have decided, as a group, to not offer therapy to women with stage 4- triple negative lesions. Survival is so low, you … Continue reading
Should we try?
Arnolds M, et al. Worth a Try? Describing the Experiences of Families during the Course of Care in the Neonatal Intensive Care Unit When the Prognosis is Poor. The Journal of pediatrics. 2018;196:116-22 e3. A few times a year many … Continue reading
Active intervention at 22 weeks gestation, is it futile?
In order to respond to the question posed in the title we need first to agree on what “futile” means. It could mean “it never works” or, “it can work but the ultimate result is so bad that it isn’t … Continue reading
New Published Letter, a response to the ‘number needed to suffer’.
The new issue of Acta Paediatrica (Februray 2018) includes a letter I wrote in response to a commentary written by a paediatric anaesthetist, Dr Lönnqvist. If you receive an email with a description of the contents of each issue, as … Continue reading
Time to abandon the Papile classification? (part 2)
As I mentioned in the last post, the initial report of outcomes by Bassan and others showed that the infants with severity score 0, (unilateral haemorrhage without midline shift affecting one zone) had reasonably good outcomes, 7 of 8 had … Continue reading
Posted in Neonatal Research
Tagged Ethics, intracranial hemorrhage, long term outcomes, mortality
2 Comments
