Tag Archives: Ethics

What do we tell families at 22 weeks?

When we counsel families about the potential outcomes for infants born profoundly preterm, I think we would all agree that we should be honest, transparent and truthful. Which includes, I would suggest, truthfulness about our own local results, as well … Continue reading

Posted in Neonatal Research | Tagged , , | Leave a comment

Active intensive care at 22 weeks gestation

Even the New England Journal are getting in on the act (Lee CD, et al. Neonatal Resuscitation in 22-Week Pregnancies. N Engl J Med. 2022;386(4):391-3), I guess that someone talked to the editors about the practice variation in resuscitation of … Continue reading

Posted in Neonatal Research | Tagged , , | 2 Comments

Survival and outcomes for the extremely preterm. The NICHD network results continue to improve: Can we do even better?

A new publication from the NRN describes short term outcomes and care practices of babies from 22 to 28 weeks gestation born in recent years (2013 to 2018) and for those born in 2013-2016 results of evaluations of those followed … Continue reading

Posted in Neonatal Research | Tagged , , , , , , , | Leave a comment

Ethically acceptable pain research

Just imagine for a moment that you are the parent of Jo, who is 4 years old, Jo has a sudden onset of breathlessness and the investigations in the Emergency Room show a spontaneous pneumothorax, that needs a drain. You … Continue reading

Posted in Neonatal Research | Tagged , , , | 1 Comment

Unethical pain research in the newborn. A list of shame.

Unethical pain studies are still being published, in journals which include several from mainstream publishing houses. In these studies published recently and appearing on-line in recent weeks, newborn infants were assigned by the researchers to experience pain. The reviewers of … Continue reading

Posted in Neonatal Research | Tagged , , , | 2 Comments

How do we make decisions for the most immature babies, with their families?

Although babies under 25 weeks account for a tiny proportion of births, and a small proportion of NICU admissions, the importance of the question asked in the title can be seen by the ongoing number of publications, below are just … Continue reading

Posted in Neonatal Research | Tagged , , , , | 1 Comment

How often does Whole Genome Sequencing really help the baby? Or their family?

It is a long time since I have written anything on this blog about the above issue, I have an article in submission to the real scientific literature with some illustrious co-authors, but I was prompted to write this blog … Continue reading

Posted in Neonatal Research | Tagged , | Leave a comment

Pain studies with untreated control groups in babies are unethical.

If you are performing a study of pain control in the newborn and you assign babies to untreated controls, you are creating unnecessary avoidable pain in the control patients. That is true for any patient who is incompetent, obviously including … Continue reading

Posted in Neonatal Research | Tagged , , , | 2 Comments

Two amazing trials, at the opposite ends of the spectrum. What a weird world.

In the most recent NEJM two trials impacting newborn/paediatric care. One including 3,211 preterm infants, which shows that a very simple intervention could save, I estimate, tens of thousands of lives each year at almost no cost; the other with … Continue reading

Posted in Neonatal Research | Tagged , | 1 Comment

Do estimates of survival change decisions made?

Kidszun A, et al. Effect of Neonatal Outcome Estimates on Decision-Making Preferences of Mothers Facing Preterm Birth: A Randomized Clinical Trial. JAMA Pediatr. 2020. This is a short report of an interesting idea, published as a research letter. The authors … Continue reading

Posted in Neonatal Research | Tagged | 1 Comment