Tag Archives: Randomized Controlled Trials

Are preterm babies frequently Iodine deficient?

Williams F, et al. Supplemental Iodide for Preterm Infants and Developmental Outcomes at 2 Years: an RCT. Pediatrics. 2017. We all need some iodine in order to make thyroid hormones (iodine doesn’t actually do anything else for us as far … Continue reading

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Early low dose hydrocortisone seems to not affect medium term development; PREMILOC outcomes at 22 months.

The PREMILOC trial was a multi-center RCT of hydrocortisone, 0.5mg/kg twice per day for 7 days followed by 0.5 mg/kg per day for 3 days, given starting within 24 hours of age to infants of 24 to less than 28 … Continue reading

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Fluid restriction to prevent BPD?

In response to my previous post, one of the comments was a question about fluid volumes in the first few days of life, and whether fluid and/or sodium intake was important for the development of BPD during the early neonatal … Continue reading

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Fluid restriction as treatment for BPD? This time with the summary of findings table.

I realize that many of my gentle readers may not have access to the Cochrane reviews in full text as soon as they are published. The NICHD do provide free access to the neonatal reviews, (together with a useful introduction … Continue reading

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New Publication: Does fluid restriction improve the clinical status of babies with BPD?

I have never been convinced that fluid restriction is a good thing for kids with BPD. I think the common practice came about because of the short-term improvements in lung function that sometimes follow if you start diuretics. The idea … Continue reading

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Should we freeze maternal breast milk in the NICU? Pasteurize it?

Maternal breast milk is what we should be giving to every preterm infant as much as possible. But we know that there are cases of transmission of cytomegalovirus (CMV) and reports of transmission of other pathogens to babies from breast … Continue reading

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Happy New Review no. 2; Inhaled NO in the full term infant

We have also updated the Cochrane review of inhaled NO in the term infant. (Barrington KJ, Finer N, Pennaforte T, Altit G. Nitric oxide for respiratory failure in infants born at or near term. Cochrane database of systematic reviews (Online). … Continue reading

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