Tag Archives: Randomized Controlled Trials

Death or oxygen, which is worse?

We have a big problem in neonatal research. We have constructed composite outcomes that have become the “standard of design”, but are not of much use for anyone. Because we are, rightly, concerned that death and other diagnoses may be … Continue reading

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Under Pressure…

This post “under pressure” isn’t about the classic collaboration between David Bowie and Queen at Live Aid, rather it is about how to wean CPAP. Should we trial preterm babies off for a period every day, or either progressively reduce … Continue reading

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Heads up?

A new RCT published in the Journal of Perinatology suggests that a midline head position with head elevated at 30 degrees might reduce severe intracranial hemorrhage. (Kochan M, et al. Elevated midline head positioning of extremely low birth weight infants: … Continue reading

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Surfactant by nebulisation

After the PAS meeting I blogged about a presented abstract of nebulized lucinactant, which showed a possible reduction in needing intubation among babies on CPAP who received the surfactant, compared to controls. A new publication from Perth (Minocchieri S, et … Continue reading

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Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM

The NeoProm primary publication is the result of a prolonged gestation; I remember meetings over 15 years ago when Cynthia Cole from Boston was suggesting the idea, and although she was not, I think, finally an author on any of … Continue reading

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Even more thoughts on breast milk fortification

I thought I would discuss the new study by O’Connor and colleagues in a little more detail (O’Connor DL, et al. Nutrient enrichment of human milk with human and bovine milk-based fortifiers for infants born weighing <1250 g: a randomized … Continue reading

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Just needle it! #NeoEBM

I didn’t post much about last year’s PAS (and I am not sure I will have the energy in future years either) there are often disappointments and surprises, abstrracts presented as platforms in important sessions that should not have been, … Continue reading

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