Tag Archives: Analgesia

The FDA warns against anaesthesia in the very young

Posted on 10 February 2017 by keithbarrington

There has been accumulating evidence of the potential risks of anaesthetic agents, such as risks of enhanced apoptosis in animal models and long-term functional effects in  those various animal models also. All anaesthetic agents appear to be affected, which I … Continue reading →

Posted in Neonatal Research | Tagged , | 3 Comments

Many unethical pain studies in newborns

Posted on 23 September 2015 by keithbarrington

Carlo Bellieni and Celeste Johnston (Conflict of Interest flag, I have collaborated with both of them) have just reviewed a couple of recent years research of analgesic interventions in the newborn. Of 46 randomized studies of painful procedures, 70% had … Continue reading →

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Pain is bad for you, sucrose makes it better (even if you are a rat).

Posted on 2 September 2015 by keithbarrington

I rarely discuss animal research in this blog, but occasionally something striking stimulates a new post. I have discussed sucrose not that long ago, in particular I emphasized the over-interpretation of a secondary analysis of a non-randomized comparison of very … Continue reading →

Posted in Neonatal Research | Tagged , , | 6 Comments

Long term effects of surgery in the infant

Posted on 18 June 2015 by keithbarrington

To follow on from a study in a recent “neonatal updates”, there is a new publication from an Australian group that have been pursuing a prospective cohort of full term infants who had major surgery in the first 90 days … Continue reading →

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Recent pain/analgesia articles

Posted on 17 June 2015 by keithbarrington

Several very recent articles have addressed issues of pain and analgesia in the newborn. van Ganzewinkel CJ, et al. Chronic pain in the newborn: toward a definition. The Clinical journal of pain. 2014;30(11):970-7. This article describes a consensus building expert-based … Continue reading →

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Neonatal Updates

Posted on 11 June 2015 by keithbarrington

Deshmukh M, et al. Effect of gastric lavage on feeding in neonates born through meconium-stained liquor: a systematic review. Archives of Disease in Childhood – Fetal and Neonatal Edition. 2015. When I first went to one of the hospitals I … Continue reading →

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Echocardiography is painless

Posted on 11 June 2015 by keithbarrington

Lavoie PM, et al. Oral glucose during targeted neonatal echocardiography: is it useful? Archives of Disease in Childhood – Fetal and Neonatal Edition. 2015. Echocardiography can sometimes disturb unstable babies. In this randomized controlled trial the investigators wanted to see … Continue reading →

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The Power of Parent’s Touch.

Posted on 5 December 2014 by keithbarrington

My friend and colleague Marsha Campbell-Yeo is part of the Centre for Pediatric Pain research. She has just produced a video about controlling pain in young babies, which you can see here: My only beef is that all the parents … Continue reading →

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Pain control for intubation by trainees

Posted on 4 September 2014 by keithbarrington

Because of my research interest in premedication for endotracheal intubation I have been asked several times to talk to groups about the subject, I have often been asked whether intubations by trainees should be premedicated, because their risk of failed … Continue reading →

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Doing research using Youtube

Posted on 12 June 2014 by keithbarrington

When my kids went to have their immunizations we took some sucrose solution with us to the hospital (don’t ask me how we came to have sucrose solution, its a secret) and were ready to either have the immunizations done … Continue reading →

Posted in Neonatal Research | Tagged , | 1 Comment