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Tag Archives: Analgesia
The FDA warns against anaesthesia in the very young
There has been accumulating evidence of the potential risks of anaesthetic agents, such as risks of enhanced apoptosis in animal models and long-term functional effects in those various animal models also. All anaesthetic agents appear to be affected, which I … Continue reading
Many unethical pain studies in newborns
Carlo Bellieni and Celeste Johnston (Conflict of Interest flag, I have collaborated with both of them) have just reviewed a couple of recent years research of analgesic interventions in the newborn. Of 46 randomized studies of painful procedures, 70% had … Continue reading
Posted in Neonatal Research
Tagged Analgesia, Ethics, pain, Randomized Controlled Trials
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Pain is bad for you, sucrose makes it better (even if you are a rat).
I rarely discuss animal research in this blog, but occasionally something striking stimulates a new post. I have discussed sucrose not that long ago, in particular I emphasized the over-interpretation of a secondary analysis of a non-randomized comparison of very … Continue reading
Long term effects of surgery in the infant
To follow on from a study in a recent “neonatal updates”, there is a new publication from an Australian group that have been pursuing a prospective cohort of full term infants who had major surgery in the first 90 days … Continue reading
Recent pain/analgesia articles
Several very recent articles have addressed issues of pain and analgesia in the newborn. van Ganzewinkel CJ, et al. Chronic pain in the newborn: toward a definition. The Clinical journal of pain. 2014;30(11):970-7. This article describes a consensus building expert-based … Continue reading
Neonatal Updates
Deshmukh M, et al. Effect of gastric lavage on feeding in neonates born through meconium-stained liquor: a systematic review. Archives of Disease in Childhood – Fetal and Neonatal Edition. 2015. When I first went to one of the hospitals I … Continue reading
Echocardiography is painless
Lavoie PM, et al. Oral glucose during targeted neonatal echocardiography: is it useful? Archives of Disease in Childhood – Fetal and Neonatal Edition. 2015. Echocardiography can sometimes disturb unstable babies. In this randomized controlled trial the investigators wanted to see … Continue reading
