-
Recent Posts
breathe, baby, breathe
-
Join 10,279 other subscribers
- Analgesia
- anemia
- antenatal steroids
- antibiotics
- anticonvulsants
- Apnea
- asphyxia
- Assisted ventilation
- BPD
- breast milk
- caffeine
- CMV
- Conflicts of Interest
- Congenital Heart Disease
- Convulsions
- CPAP
- Delayed Cord Clamping
- diaphragmatic hernia
- EEG
- End-of-life decisions
- endotracheal intubation
- enteral feeding
- erythropoietin
- Ethics
- families
- Fluids
- Gastro-oesophageal reflux
- Genetic tests
- Global Neonatal Health
- Handicap
- Head Ultrasound
- Health Care Organization
- Heart Surgery
- Hemodynamics
- High-Flow cannula
- Hyperglycemia
- Hypoglycemia
- Hypotension
- Hypothermia
- hypoxic ischemic encephalopathy
- infection control
- intracranial hemorrhage
- Lactoferrin
- long term outcomes
- lung compliance
- microbiome
- mortality
- MRI
- Necrotising Enterocolitis
- Nitric Oxide
- nutrition
- Obstetrics
- oxygen therapy
- oxygen toxicity
- pain
- Parenteral Nutrition
- PDA
- Prebiotics
- Preventing Prematurity
- Probiotics
- pulmonary physiology
- Randomized Controlled Trials
- Research Design
- respiratory support
- Resuscitation
- Retinopathy of Prematurity
- Sepsis
- statistics
- steroids
- surfactant treatment
- Survival
- Systematic Reviews
- transfusion
- trisomy
- twins
Respire, bébé, respire!
RSS Links
Canadian Premature Babies Foundation
Sainte Justine Hospital
Canadian Neonatal Network
Préma-Québec
Categories
Transport Néonatal
Archives
- January 2023
- December 2022
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- January 2022
- October 2021
- September 2021
- August 2021
- May 2021
- April 2021
- January 2021
- December 2020
- October 2020
- September 2020
- August 2020
- July 2020
- May 2020
- April 2020
- March 2020
- February 2020
- January 2020
- December 2019
- November 2019
- October 2019
- September 2019
- June 2019
- May 2019
- April 2019
- March 2019
- February 2019
- December 2018
- November 2018
- October 2018
- June 2018
- May 2018
- April 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- December 2015
- November 2015
- October 2015
- September 2015
- August 2015
- June 2015
- May 2015
- April 2015
- March 2015
- February 2015
- January 2015
- December 2014
- November 2014
- October 2014
- September 2014
- August 2014
- June 2014
- May 2014
- April 2014
- March 2014
- February 2014
- January 2014
- December 2013
- November 2013
- October 2013
- September 2013
- August 2013
- July 2013
- June 2013
- May 2013
- April 2013
- March 2013
- February 2013
- January 2013
- December 2012
- November 2012
- October 2012
- September 2012
- August 2012
- July 2012
- June 2012
- May 2012
Meta
Tag Archives: Analgesia
Time to stop placebo injections in neonatal research projects
Randomized controlled trials are the bedrock of evidence-based medicine. If a treatment has a good theoretical rationale, and preclinical data showing efficacy, the only way to prove efficacy in the human is to randomise patients to the treatment, compared to … Continue reading
Evidence-based neonatology, or science based neonatology?
To many followers of this blog, the title may seem a little strange; is there any difference? Surely science underlies all of our field, and testing treatments in adequately designed trials leads to progressive improvements through the application of evidence-based … Continue reading
Skin to skin contact reduces pain… in mothers!
Some neonatal interventions for pain relief don’t seem to work in older subjects, sucrose for example doesn’t seem effective out of the neonatal period, a study from our Emergency Room showed no benefit of sucrose for bladder catheterisation in infants … Continue reading
Ethically acceptable pain research
Just imagine for a moment that you are the parent of Jo, who is 4 years old, Jo has a sudden onset of breathlessness and the investigations in the Emergency Room show a spontaneous pneumothorax, that needs a drain. You … Continue reading
Unethical pain research in the newborn. A list of shame.
Unethical pain studies are still being published, in journals which include several from mainstream publishing houses. In these studies published recently and appearing on-line in recent weeks, newborn infants were assigned by the researchers to experience pain. The reviewers of … Continue reading
Babies feel pain, and they remember it!
I usually don’t post about studies of painful procedures where there was no analgesic prophylaxis in some of the the subjects, except to criticize them, and if they are recent, to call for their retraction. So when I first saw … Continue reading
Pain studies with untreated control groups in babies are unethical.
If you are performing a study of pain control in the newborn and you assign babies to untreated controls, you are creating unnecessary avoidable pain in the control patients. That is true for any patient who is incompetent, obviously including … Continue reading
The FDA warns against anaesthesia in the very young
There has been accumulating evidence of the potential risks of anaesthetic agents, such as risks of enhanced apoptosis in animal models and long-term functional effects in those various animal models also. All anaesthetic agents appear to be affected, which I … Continue reading
Many unethical pain studies in newborns
Carlo Bellieni and Celeste Johnston (Conflict of Interest flag, I have collaborated with both of them) have just reviewed a couple of recent years research of analgesic interventions in the newborn. Of 46 randomized studies of painful procedures, 70% had … Continue reading
Posted in Neonatal Research
Tagged Analgesia, Ethics, pain, Randomized Controlled Trials
Leave a comment
Pain is bad for you, sucrose makes it better (even if you are a rat).
I rarely discuss animal research in this blog, but occasionally something striking stimulates a new post. I have discussed sucrose not that long ago, in particular I emphasized the over-interpretation of a secondary analysis of a non-randomized comparison of very … Continue reading
Neonatal Research 