Monthly Archives: June 2016

Causes and Consequences of Bronchopulmonary Dysplasia

Posted on 21 June 2016 by Keith Barrington

Sullivan K, et al. The Association between Positive Tracheal Aspirate Cultures and Adverse Pulmonary Outcomes in Preterm Infants with Severe Bronchopulmonary Dysplasia. American journal of perinatology. 2016(EFirst).  This is an interesting study, with many limitations. 121 intubated VLBW preterm infants … Continue reading →

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Survival and outcomes of extremely immature babies, glass half empty or…

Posted on 17 June 2016 by Keith Barrington

Anderson JG, et al. Survival and Major Morbidity of Extremely Preterm Infants: A Population-Based Study. Pediatrics. 2016. This publication is derived from data in a public health database, the data for which comes from ICD-9 codes of the hospital discharge … Continue reading →

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Moral Distress among nurses (and others).

Posted on 15 June 2016 by Keith Barrington

This publication appeared on-line a couple of months ago, and still isn’t in print. Prentice T, et al. Moral distress within neonatal and paediatric intensive care units: a systematic review. Arch Dis Child. 2016. It is a systematic review from Melbourne, … Continue reading →

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Neonatal nurses save lives, if you have enough of them.

Posted on 13 June 2016 by Keith Barrington

In the UK an “intensive care” day for a newborn is defined as a day where the baby is intubated and ventilated, or is on non-invasive respiratory support (CPAP of non-invasive ventilation) AND parenteral nutrition, or on the day of … Continue reading →

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Is your brain really necessary?

Posted on 13 June 2016 by Keith Barrington

I remember years ago watching a BBC documentary (I think it was BBC) with the tabloid-type title “is your brain really necessary?” it focused on patients with severe hydrocephalus who had normal neurological examinations and normal intellect. One was, if I … Continue reading →

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Lactoferrin again, this time the human kind

Posted on 10 June 2016 by Keith Barrington

Sherman MP, et al. Randomized Controlled Trial of Talactoferrin Oral Solution in Preterm Infants. The Journal of pediatrics. 2016. This should be characterized as a pilot trial, as there were only 60 patients per group, and as a trial of … Continue reading →

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RV function in BPD

Posted on 9 June 2016 by Keith Barrington

Sehgal A, et al. Right Ventricular Function in Infants with Bronchopulmonary Dysplasia: Association with Respiratory Sequelae. Neonatology. 2016;109(4):289-96. Babies with BPD frequently have some degree of pulmonary hypertension, which may lead to right ventricular dysfunction. Arvind Seghal and colleagues studied … Continue reading →

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Caffeine protects the lungs

Posted on 7 June 2016 by Keith Barrington

From the CAP trial we know that caffeine administration leads to less bronchopulmonary dysplasia. The question is how? The mechanism could help to design other studies, or help in a decision about clinical use where the question hasn’t been directly … Continue reading →

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Tattoos, Beer and Bow-ties, a worthy follow up to “Pepperoni Pizza and sex”

Posted on 7 June 2016 by Keith Barrington

Annie Janvier has just had another article published on-line, in JAMAPediatrics. The full title is “Tattoos, Beer, and Bow Ties: The Limits of Professionalism in Medicine”  It tells of a day when she met a patient’s father for the first time … Continue reading →

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Meta-analysis of the oxygen trials, including the long term outcomes

Posted on 6 June 2016 by Keith Barrington

This new publication is not a complete systematic review, but is a review of the history, design and outcomes of the oxygen saturation targeting trials, and of the early stopping of 2 trials. Stenson BJ. Oxygen Saturation Targets for Extremely Preterm … Continue reading →

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