Tag Archives: Necrotising Enterocolitis

Donor human milk for congenital heart disease?

Newborns with serious Congenital Heart Disease are at risk of intestinal injury which may present in a similar fashion to Necrotising Enterocolitis (NEC). Our local guidelines for eligibility for donor milk from our provincial milk bank include infants with significant … Continue reading

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How fast to feed?

One of the recurring themes in this blog is that good, large enough, prospective RCTs do not necessarily reproduce the results of prior smaller trials, and often do not reproduce the findings of observational studies. Specifically, I have mentioned previously … Continue reading

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Why is MOM best? part 2

MOM is best, because it leads to the lowest incidence of NEC; but why? (if you didn’t read part 1, MOM is Mother’s Own Milk) The impacts of milk processing which create the differences in milk composition, detailed in my … Continue reading

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Why is MOM best?

Mother’s Own Milk (MOM) seems to be the best base for enteral nutrition of the preterm infant, in terms of the risk of infection, the risk of Enterocolitis (NEC) and, probably, long term neurodevelopment. Reasonably good data show that replacing … Continue reading

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Measure gastric residuals? Safe to stop?

A new RCT published in JAMA pediatrics compared growth and other clinical outcomes between infants <33 weeks gestation and <1250g who were managed with routine gastric residual measurements or without. (Parker LA, et al. Effect of Gastric Residual Evaluation on … Continue reading

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Do transfusions trigger NEC? or does anemia?

I am still unconvinced that transfusion associated NEC is a real thing, I think it is possibly a real phenomenon, but I am not sure how to know for sure. Some of the best evidence I think comes from the … Continue reading

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Prebiotics and preterms and probiotics.

A selection of recent publications, regarding the issues in the title, that I find interesting and which seem to tell a consistent story. From Nick Embleton’s group the following interesting study (Stewart CJ, et al. Longitudinal development of the gut … Continue reading

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