Tag Archives: Necrotising Enterocolitis

Is breast-milk really best?

Although many people (including myself) are convinced that human breast milk is the preferable nutrition for human babies, including the preterm, some of the evidence regarding benefits is shaky. For example the evidence that breast milk feeding reduces late-onset sepsis. … Continue reading

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Necrotizing Enterocolitis: manipulating the microbiome, part 3

Abdulkadir B, et al. Stool bacterial load in preterm infants with necrotising enterocolitis. Early Hum Dev. 2016;95:1-2.  More work from the Newcastle group, this time the group decided not to look at the proportion of different bugs in the stools, … Continue reading

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Necrotizing Enterocolitis: manipulating the microbiome, part 2

The Newcastle, UK, group has published an article about the intestinal microbiome of babies receiving routine probiotic prophylaxis. Abdulkadir B, et al. Routine Use of Probiotics in Preterm Infants: Longitudinal Impact on the Microbiome and Metabolome. Neonatology. 2016;109(4):239-47. The authors studied 7 … Continue reading

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Necrotizing Enterocolitis: manipulating the microbiome, part 1

Some very interesting recent publications about NEC, so I will post a multi-part bumper posting. The first has just been published (in tomorrow’s Lancet) Warner BB, et al. Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective … Continue reading

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PPIs are toxic

PPIs could mean “public-private initiatives” which are highly toxic, as recent experience in the UK and in Quebec has shown, but in this case I mean proton pump inhibitors. Stark CM, Nylund CM. Side Effects and Complications of Proton Pump … Continue reading

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Prebiotics, Probiotics and the microbiome

A series of interesting recent articles: Yang J, et al. Application of Laser Capture Microdissection and 16S rRNA Gene Polymerase Chain Reaction in the Analysis of Bacteria Colonizing the Intestinal Tissue of Neonates With Necrotizing Enterocolitis. Pediatr Infect Dis J. … Continue reading

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Do Blood transfusions trigger NEC? This month the answer is no.

OK, not exactly this month, but “towards the end of last year” wouldn’t have been as good a title. Three case-control studies, with some differences in design and implementation, but all 3 with the same result, no evidence that red … Continue reading

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