Tag Archives: Necrotising Enterocolitis

Antibiotics are dangerous, unless you actually need them.

In response to my previous post Claus Klingenberg wrote a comment in which he mentioned a recent systematic review that he had published with a group of colleagues. This review of a small number of RCTs (9) and a larger … Continue reading

Posted in Neonatal Research | Tagged , , , | Leave a comment

Probiotics for extremely preterm infants

The use of probiotics for Necrotising enterocolitis prophylaxis in the very preterm is increasing across Canada. There are apparently, though, centers that will only give them to larger preterm infants, and not to the most immature. I think that is … Continue reading

Posted in Neonatal Research | Tagged , , , | 2 Comments

It doesn’t make much difference how often we feed babies

Over the years there have a number of studies comparing two different feeding regimes. Most recently there has been a comparison of 2 hourly vs 3 hourly feeds and a comparison of feeds every 3 hours compared to 4 feeds … Continue reading

Posted in Neonatal Research | Tagged , , , | Leave a comment

Hey, doctor, leave those guts alone!

Intestinal function is often sluggish after preterm delivery. Establishing early enteral nutrition, the goal of all of us, is interrupted often by repeated regurgitation, or large residuals (if you measure them) or abdominal distension. There are also reported correlations between … Continue reading

Posted in Neonatal Research | Tagged , , , | 4 Comments

Is breast-milk really best?

Although many people (including myself) are convinced that human breast milk is the preferable nutrition for human babies, including the preterm, some of the evidence regarding benefits is shaky. For example the evidence that breast milk feeding reduces late-onset sepsis. … Continue reading

Posted in Neonatal Research | Tagged , , , , | 6 Comments

Necrotizing Enterocolitis: manipulating the microbiome, part 3

Abdulkadir B, et al. Stool bacterial load in preterm infants with necrotising enterocolitis. Early Hum Dev. 2016;95:1-2.  More work from the Newcastle group, this time the group decided not to look at the proportion of different bugs in the stools, … Continue reading

Posted in Neonatal Research | Tagged , , , , | 2 Comments

Necrotizing Enterocolitis: manipulating the microbiome, part 2

The Newcastle, UK, group has published an article about the intestinal microbiome of babies receiving routine probiotic prophylaxis. Abdulkadir B, et al. Routine Use of Probiotics in Preterm Infants: Longitudinal Impact on the Microbiome and Metabolome. Neonatology. 2016;109(4):239-47. The authors studied 7 … Continue reading

Posted in Neonatal Research | Tagged , | 2 Comments