Tag Archives: Hypoglycemia

Antenatal steroids prior to late preterm delivery; still many questions, but a major shift in practice.

It can sometimes take years for major advances in medicine, based on clear evidence of improved outcomes, to lead to shifts in practice. One example is the initial demonstration by Liggins and Howie that antenatal steroids (ANS) improved survival of … Continue reading

Posted in Neonatal Research | Tagged , , , | 3 Comments

We need to rethink neonatal hypoglycaemia

A great deal of time and effort is expended to detect and treat low blood sugars in the newborn. Studies to determine risk factors, monitoring schedules, and treatment strategies have taken a great deal of effort, and implementing the recommended … Continue reading

Posted in Neonatal Research | Tagged , | 2 Comments

Hypoglycaemia, symptomatic or non-?

Many algorithms for detection and treatment of hypoglycaemia make a big deal of whether the hypoglycaemia is symptomatic or not. Symptomatic hypoglycaemia is supposed to be more dangerous in the long term, and requires more aggressive treatment. But symptoms accredited … Continue reading

Posted in Neonatal Research | Tagged | 2 Comments

Glucose screening and treatment in the newborn; what now?

This is a field that stagnated in darkness for a while, “But, soft! what light through yonder window breaks? It is the east, and science is the sun” (with apologies to Romeo). Recent research has shown that 1. In healthy … Continue reading

Posted in Neonatal Research | Tagged | Leave a comment

Let it GLOW… Normal blood sugar profiles in newborn infants.

To stay with this recent “hot topic” of this blog; what low blood sugar threshold should be used for intervention in the neonatal period? The usual risk factors (SGA, LGA, IDM, late preterm, maternal beta-blockers) select a group of babies … Continue reading

Posted in Neonatal Research | Tagged | 3 Comments

What is hypoglycaemia? Part 3. Part of the answer!

The only way that we can find the answer to the question of what threshold blood sugar we should use to treat babies with low blood sugars is a prospective RCT, and Behold! Look! Lo! How say you? (van Kempen … Continue reading

Posted in Neonatal Research | Tagged , , | 5 Comments

What is hypoglycemia? part 2

The new statement from the CPS, and many others, don’t discuss which measurement that we are really interested in, is it blood glucose, or plasma glucose? The different data sources are discussed as if they were all measuring the same … Continue reading

Posted in Neonatal Research | Tagged , | 1 Comment

What is hypoglycaemia? Part 1.

The Canadian Pediatric Society has just published new guidance for screening and treatment of infants at risk for neonatal hypoglycaemia. The older statement needed to be revised, in particular to include the use of oral glucose gel as an option, … Continue reading

Posted in Neonatal Research | Tagged , | 2 Comments

Glucose gel for hypoglycemia in at-risk babies? Prophylaxis no, treatment yes!

In the ongoing story of how and when to treat lower than average blood sugars in at-risk newborn infants, some clarity for some points is emerging. We know the following: 1. some babies have lower blood sugars than others (!) … Continue reading

Posted in Neonatal Research | Tagged | 8 Comments

Can we stop worrying about neonatal hypoglycaemia?

In the same, neonatal, issue of the Formerly Prestigious New England Journal of Medicine as my recent post about inhaled steroids, is a fascinating cohort study of serial blood glucose monitoring in 404 at-risk term infants (the CHYLD study). The infants … Continue reading

Posted in Neonatal Research | Tagged , | 3 Comments