Monthly Archives: May 2019

What respiratory outcomes are important?

Posted on 31 May 2019 by Keith Barrington

When bronchopulmonary dysplasia was first described by Northway in 1967 he didn’t try to produce a definition, his paper was a description of a small number of preterm survivors of high oxygen and positive pressure ventilation. He noted some years … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

High-flow in non-tertiary neonatal units: Hunting for answers. #EBNEO

Posted on 27 May 2019 by Keith Barrington

I think Brett Manley is going for the record as the person with the highest proportion of his publications in the FPNEJM, he now has 3, with 2 of them as first author. This is the HUNTER trial where babies … Continue reading →

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Research Outcomes in Neonatology : must do better.

Posted on 24 May 2019 by Keith Barrington

When planning a research project with neonatal patients the first question should be, what am I investigating? The PICO outline : standing for Patients, Intervention, Controls (or comparison) and Outcome, is a standardized way of asking the simple question. If … Continue reading →

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Just do it! Who should go home on oxygen?

Posted on 15 May 2019 by Keith Barrington

A new guideline from the ATS has been published, which gives guidelines for home oxygen therapy for children, one large group of which is, of course, babies with bronchopulmonmary dysplasia. Hayes D, Jr., et al. Home Oxygen Therapy for Children. … Continue reading →

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RCTs prevail: Antibiotic impregnation of central lines doesn’t reduce sepsis.

Posted on 9 May 2019 by Keith Barrington

In older children and adults who need central venous access, using catheters impregnated with stuff that kills bugs decreases invasive sepsis rates. A multicentre trial in English PICUs showed a reduction in sepsis from 4% to 1% when antibiotic impregnated … Continue reading →

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Putting steroids in the lungs? Still unclear if it is safe or effective.

Posted on 7 May 2019 by Keith Barrington

Systematic reviews, and meta-analyses should help us make a clinical decision, by accumulating all the evidence, determining its quality, and synthesizing impacts, we can then decide which therapeutic option to pursue. This latest review answers the following question “should I … Continue reading →

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Insulin like growth factor: does it prevent BPD, or does it increase RoP and mortality?

Posted on 1 May 2019 by Keith Barrington

In the March print edition of the Journal of Pediatrics, the report of the Insulin-like growth factor 1/IGF binding protein 3 trial, as a preventive for retinopathy. Ley D, et al. rhIGF-1/rhIGFBP-3 in Preterm Infants: A Phase 2 Randomized Controlled … Continue reading →

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