Tag Archives: Sepsis

Neonatal Sepsis after Chorioamnionitis, what to do about healthy appearing newborns

In 2007, when I was chair of the CPS Fetus and Newborn Committee, we published a guideline regarding the approach to term and late preterm infants with perinatal risk factors for sepsis. Obviously any infant with clinical signs consistent with … Continue reading

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Culture negative sepsis: what is it?

One of the things that I have wondered about over the years is whether infants who appear to be infected, but who have negative cultures, might have viral infections. A new study suggests that this is not rare. Kidszun A, et … Continue reading

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The microbiome of plastic tubes in children

Petersen SM, et al. Nasogastric feeding tubes from a neonatal department yield high concentrations of potentially pathogenic bacteria – even one day after insertion. Pediatr Res. 2016.  These authors cultured 94 nasogastric feeding tubes from 34 preterm infants. 1 ml … Continue reading

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Is breast-milk really best?

Although many people (including myself) are convinced that human breast milk is the preferable nutrition for human babies, including the preterm, some of the evidence regarding benefits is shaky. For example the evidence that breast milk feeding reduces late-onset sepsis. … Continue reading

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TPN toxic?

Humans, after they are born, are supposed to receive their nutrition via the gut. Before that of course, they receive a continuous infusion of nutrition via the umbilical vein. We are far from having an intravenous nutrition mixture for sick … Continue reading

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Lacuna trial now in print

Now available on-line the pilot trial of lactoferrin prophylaxis that I performed at Sainte Justine. (Barrington KJ, Assaad M-A, Janvier A. The Lacuna Trial: a double-blind randomized controlled pilot trial of lactoferrin supplementation in the very preterm infant. J Perinatol. … Continue reading

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When to deliver after Preterm Ruptured Membranes

I have often wondered why my obstetrical colleagues would often induce labour once a woman with ruptured membranes reached 34 weeks. I wasn’t aware of any data to support doing this, or, on the other hand, any good data to … Continue reading

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