Tag Archives: Preventing Prematurity

Progesterone doesn’t prevent prematurity?

Progesterone analogues, including 17-OH progesterone caproate have been investigated over the last several years for prevention of prematurity. In the pivotal trial from 2003 17OHPC intramuscularly once per week was shown to reduce prematurity at less than 37 weeks, less … Continue reading

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Are we Civilized?

I have always thought that one very important test of a truly civilized culture is how a society treats those who are less fortunate. An editorial in the Lancet (thanks to Nick Embleton for alerting me to it) takes up … Continue reading

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Cervical pessaries? Really?

A new study in the Lancet is a multi-center RCT of the use of a cervical pessary to reduce preterm delivery in twin pregnancies. I must say this sounded a bit unlikely to me, but it turns out there just … Continue reading

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One Babe at a Time: ART and a multiplicity of multiples

I have just written a review article which is in the submission revision process for a journal that shall remain nameless (I don’t know why, but that is the tradition, you don’t say which journal, until it gets accepted) It … Continue reading

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Tocolytics and Network meta-analysis

What do you do if you want to know what is the best treatment for a condition, and treatment A and treatment B have both been compared to placebo, but have never been compared to each other in RCTs? If … Continue reading

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Perinatal outcomes of IVF twins

Another post about twins and IVF. I’ll back off soon, I promise. A systematic review published just last year notes that the outcomes of twins conceived after IVF is worse than those who are conceived naturally. (Rossi AC, D’Addario V. … Continue reading

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Preventing Prematurity

We’ve known for a while that progesterones can reduce prematurity in certain situations. Intramuscular 17 hydroxy progesterone caproate reduces prematurity in women who have had a previous premature baby. (Meis’s article link below) Now a systematic review of intravaginal progesterone … Continue reading

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