Monthly Archives: August 2026

Steroid drops for retinopathy?

Posted on 11 August 2026 by Keith Barrington

A just published, modestly sized, multicentre randomized masked trial from Sweden has investigated the efficacy of dexamethasone eyedrops to prevent the progression of pre-threshold RoP. Infants born before 30 weeks’ gestational age (GA) were eligible if they had prethreshold RoP, … Continue reading →

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Study Design: Hierarchical Composite Outcomes

Posted on 7 August 2026 by Keith Barrington

As frequent readers of the blog will know, there are major concerns about using the classical dichotomous composite outcomes for trials. One of the outcomes included is usually death, as it “competes” with many other outcomes, and the other components … Continue reading →

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Not neonatology. Trip to Costa Rica

Posted on 6 August 2026 by Keith Barrington

Our family vacation this year was to Costa Rica. One week just Annie and me, then another 2 weeks with Annie’s mother and 2 of our children. Costa Rica has a well-deserved reputation as a destination for holidays with abundant … Continue reading →

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Routine vitamin K prophylaxis. Why are there so many refusals?

Posted on 6 August 2026 by Keith Barrington

This is still a fairly rare phenomenon in my hospital, but it does seem to increasing slightly here, as it is just about everywhere else. The science is settled, transplacental transfer of vitamin K is extremely limited, hepatic stores at … Continue reading →

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