Tag Archives: asphyxia

PAS 2023, some selected stuff

Posted on 8 May 2023 by Keith Barrington

Hernia repair timing One trial which will should have an impact on the care of newborn infants is the trial of early versus late hernia repair. 40 neonatal centres in the USA randomized 320 preterm infants to inguinal hernia repair … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments

Imaging after therapeutic hypothermia: when to do the MRI (if at all)

Posted on 19 April 2023 by Keith Barrington

I had thought it was well settled that imaging soon after rewarming was as good for predicting outcomes in HIE as later imaging, but it seems that the timing, and the methodology are still uncertain. Tabacaru C, et al. Diffusion … Continue reading →

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Treating seizures in the newborn: phenobarbitone unexpectedly not so bad!

Posted on 28 May 2020 by Keith Barrington

Or perhaps “probably better than the current fashionable alternative” might be a better title. Phenobarbitone (or phenobarbital, I will call it PHE) is one of the oldest anticonvulsants out there, and because of little good data, remains the drug of … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 2 Comments

How should we evaluate heart rate during neonatal resuscitation?

Posted on 28 February 2019 by Keith Barrington

Many babies receive some sort of “resuscitation” during their transition from intra-uterine to extra-uterine life. How do we decide when a baby needs intervention? A baby who is active and breathing is usually left alone, a baby who is neither … Continue reading →

Posted in Neonatal Research | Tagged , | 3 Comments

Who needs an EEG? part 2

Posted on 5 December 2018 by Keith Barrington

I realize that I didn’t answer the question in the title of the previous post. It could even seem that I think the EEG is not a very useful monitor, as many babies were inappropriately treated even when using an … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Who needs an EEG?

Posted on 30 November 2018 by Keith Barrington

Clinical neurologic evaluation of our patients in the NICU is limited; a careful detailed neurologic exam can only reveal so much in newborns who can’t cooperate or communicate. Many of our patients need ancillary testing to reveal what is going … Continue reading →

Posted in Neonatal Research | Tagged , , | 1 Comment

What to do with mild encephalopathy?

Posted on 13 November 2017 by Keith Barrington

Therapeutic hypothermia improves the chances of babies with moderate or severe hypothermia of surviving without serious disability; referrals for evaluation for therapeutic hypothermia have exploded in our center, and many others, now that this advance is widely acknowledged. Many of … Continue reading →

Posted in Neonatal Research | Tagged , , | 7 Comments

Teaching clinicians to evaluate encephalopathy

Posted on 10 November 2016 by Keith Barrington

I hope this link stays active for ever as it is a great resource… Courtney Wusthoff from Stanford has developed a web-based educational tool, designed initially, I think, for medical (pediatric) residents. Their team has evaluated whether or not this … Continue reading →

Posted in Neonatal Research | Tagged | 3 Comments

Sustained inflation during neonatal resuscitation? Not so fast…

Posted on 18 August 2016 by Keith Barrington

A sustained inflation at birth of an asphyxiated lamb which lasts 30 seconds leads to much more rapid restoration of heart rate and blood pressure than either conventional ventilation or a series of shorter sustained inflations of 5 seconds each. … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

Neonatal Updates

Posted on 16 May 2016 by Keith Barrington

Raina A, et al. Treating perinatal asphyxia with theophylline at birth helps to reduce the severity of renal dysfunction in term neonates. Acta Paediatrica. 2016. This was an RCT in 160 full-term babies with perinatal asphyxia and encephalopathy. Babies, who … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment