Tag Archives: Retinopathy of Prematurity

PAS 2018 No5: the trial with no name… propranolol for early RoP, a proper trial.

Posted on 11 May 2018 by

As far as I can see, this trial has no acronym, which isn’t a big deal, but it also doesn’t show up on trial registry searches, which is a big deal. Trials must be registered before starting them, it ensures … Continue reading →

Posted in Neonatal Research | Tagged , | 8 Comments

Does erythropoietin improve preterm babies development?

Posted on 15 March 2016 by

Ohls RK, et al. Preschool Assessment of Preterm Infants Treated With Darbepoetin and Erythropoietin. Pediatrics. 2016;137(3):1-9. Robin Ohls has been working on Erythropoietin, and its longer acting analogue darbepoietin, for many years now. As well as demonstrating that it stimulates … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

Retinopathy: up or down?

Posted on 17 November 2015 by

The oxygen saturation targeting trials showed more retinopathy with higher oxygen saturation targets. Will this translate into more retinopathy in actual practice? Many units have increased their saturation targets as a result of those studies. This may indeed lead to … Continue reading →

Posted in Neonatal Research | Tagged , , | 3 Comments

Neonatal Updates

Posted on 17 November 2015 by

Gschließer A, et al. Inter-expert and Intra-expert Agreement on the Diagnosis and Treatment of Retinopathy of Prematurity. American Journal of Ophthalmology. 2015;160(3):553-60.e3. The investigators showed 52 retinal photographs to 7 expert ophthalmologists, and then 8 weeks later showed them to … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment

NICUs are working better: still room for improvement.

Posted on 11 September 2015 by

As NICUs have become more effective, any proportional incremental improvements will necessarily get smaller, so larger and larger datasets will be needed to show any trends. The NICHD has just published data about survival and major acute morbidities among extremely … Continue reading →

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Oxygen is good for you

Posted on 28 August 2015 by

Of course you can have too much of a good thing, but you should also try and stay above the minimum. The COT trial investigators, led by Christian Poets, have published a secondary analysis of the results, examining in particular … Continue reading →

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Bevacizumab or that other more expensive one?

Posted on 2 April 2015 by

A very interesting and depressing group of articles in today’s BMJ. Retinopathy of prematurity is a small market compared to wet macular degeneration in the elderly, in whom VEGF inhibitors are proven to be extremely effective. Ranibizumab (I will call … Continue reading →

Posted in Neonatal Research | Tagged | 1 Comment