-
Recent Posts
- What outcomes matter to parents?
- Shifting the uncertainty a little further: severe early ultrasound abnormalities in the preterm. part 2
- Shifting the uncertainty: early head ultrasound abnormalities, and counselling parents. Part 1
- PAS 2023, some supplemental selected stuff
- PAS 2023, some selected stuff
breathe, baby, breathe
-
Join 10,550 other subscribers
- Analgesia
- anemia
- antenatal steroids
- antibiotics
- anticonvulsants
- Apnea
- asphyxia
- Assisted ventilation
- BPD
- breast milk
- caffeine
- CMV
- Congenital Heart Disease
- Convulsions
- CPAP
- CRP
- Delayed Cord Clamping
- diaphragmatic hernia
- EEG
- End-of-life decisions
- endotracheal intubation
- enteral feeding
- erythropoietin
- Ethics
- families
- Fluids
- Gastro-oesophageal reflux
- Genetic tests
- Global Neonatal Health
- Handicap
- Head Ultrasound
- Health Care Organization
- Heart Surgery
- Hemodynamics
- High-Flow cannula
- Hypoglycemia
- Hypotension
- Hypothermia
- hypoxic ischemic encephalopathy
- infection control
- intracranial hemorrhage
- IVH
- Lactoferrin
- long term outcomes
- lung compliance
- microbiome
- mortality
- MRI
- Necrotising Enterocolitis
- Nitric Oxide
- nutrition
- Obstetrics
- oxygen therapy
- oxygen toxicity
- pain
- Parenteral Nutrition
- PDA
- Prebiotics
- Preventing Prematurity
- Probiotics
- pulmonary physiology
- Randomized Controlled Trials
- Research Design
- respiratory support
- Resuscitation
- Retinopathy of Prematurity
- Sepsis
- statistics
- steroids
- surfactant treatment
- Survival
- Systematic Reviews
- transfusion
- trisomy
- twins
Respire, bébé, respire!
RSS Links
Canadian Premature Babies Foundation
Sainte Justine Hospital
Canadian Neonatal Network
Préma-Québec
Categories
Transport Néonatal
Archives
- May 2023
- April 2023
- February 2023
- January 2023
- December 2022
- November 2022
- October 2022
- September 2022
- August 2022
- July 2022
- June 2022
- May 2022
- April 2022
- March 2022
- January 2022
- October 2021
- September 2021
- August 2021
- May 2021
- April 2021
- January 2021
- December 2020
- October 2020
- September 2020
- August 2020
- July 2020
- May 2020
- April 2020
- March 2020
- February 2020
- January 2020
- December 2019
- November 2019
- October 2019
- September 2019
- June 2019
- May 2019
- April 2019
- March 2019
- February 2019
- December 2018
- November 2018
- October 2018
- June 2018
- May 2018
- April 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- December 2015
- November 2015
- October 2015
- September 2015
- August 2015
- June 2015
- May 2015
- April 2015
- March 2015
- February 2015
- January 2015
- December 2014
- November 2014
- October 2014
- September 2014
- August 2014
- June 2014
- May 2014
- April 2014
- March 2014
- February 2014
- January 2014
- December 2013
- November 2013
- October 2013
- September 2013
- August 2013
- July 2013
- June 2013
- May 2013
- April 2013
- March 2013
- February 2013
- January 2013
- December 2012
- November 2012
- October 2012
- September 2012
- August 2012
- July 2012
- June 2012
- May 2012
Meta
Tag Archives: Retinopathy of Prematurity
Anti VEGF treatment of retinopathy: and the long term?
There remains some doubt about the impacts on cerebral development, and thus on developmental progress of anti-VEGF treated babies. It is possible that there are cerebral effects of VEGF inhibition (or interception) and it isn’t clear what the exposure of … Continue reading
Anti-VEGF vs laser therapy for retinopathy, not worse, but not not worse?
A newer anti-VEGF drug has been invented, and evaluated in retinopathy therapy. This new drug aflibercept works differently to the “-mab” drugs we have been using. Those others are monoclonal antibodies (hence mab) directed against VEGF, whereas this new stuff … Continue reading
Posted in Neonatal Research
Tagged Randomized Controlled Trials, Retinopathy of Prematurity
1 Comment
Automated oxygen control, what’s taking so long?
A long long time ago, in a galaxy… actually quite near here, the idea of servo control of inspired oxygen was already in the air. At the time I first heard about it, the idea was to control FiO2 based … Continue reading
Does intravitreal bevacizumab adversely affect long term development? Two simultaneous systematic reviews say yes, or no.
A reliable answer to the above question would require a large multicentre RCT comparing intravitreal bevacizumab (IVB) to laser, powered for long term outcomes. Such a trial does not currently exist. As a result, 2 groups have just published systematic … Continue reading
Posted in Neonatal Research
Tagged long term outcomes, Retinopathy of Prematurity, Systematic Reviews
4 Comments
International variations in outcomes of extreme preterm infants
A publication from an international collaboration of neonatal databases has just appeared, (Lui K, et al. Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries. J Pediatr. 2019). It makes very interesting … Continue reading
Posted in Neonatal Research
Tagged intracranial hemorrhage, mortality, Retinopathy of Prematurity
1 Comment
Eye exams for fewer babies
In Canada, the current Canadian Pediatric Society recommendations, dating from 2016 are to screen infants for retinopathy of prematurity with Gestational Age <31 weeks or Birth weight <1,251 g. These recommendations are already somewhat more restrictive than other countries, in … Continue reading
Insulin like growth factor: does it prevent BPD, or does it increase RoP and mortality?
In the March print edition of the Journal of Pediatrics, the report of the Insulin-like growth factor 1/IGF binding protein 3 trial, as a preventive for retinopathy. Ley D, et al. rhIGF-1/rhIGFBP-3 in Preterm Infants: A Phase 2 Randomized Controlled … Continue reading
Posted in Neonatal Research
Tagged BPD, IGF-1, Randomized Controlled Trials, Retinopathy of Prematurity
Leave a comment
PAS 2018 No5: the trial with no name… propranolol for early RoP, a proper trial.
As far as I can see, this trial has no acronym, which isn’t a big deal, but it also doesn’t show up on trial registry searches, which is a big deal. Trials must be registered before starting them, it ensures … Continue reading
Posted in Neonatal Research
Tagged Randomized Controlled Trials, Retinopathy of Prematurity
8 Comments
Does erythropoietin improve preterm babies development?
Ohls RK, et al. Preschool Assessment of Preterm Infants Treated With Darbepoetin and Erythropoietin. Pediatrics. 2016;137(3):1-9. Robin Ohls has been working on Erythropoietin, and its longer acting analogue darbepoietin, for many years now. As well as demonstrating that it stimulates … Continue reading
Retinopathy: up or down?
The oxygen saturation targeting trials showed more retinopathy with higher oxygen saturation targets. Will this translate into more retinopathy in actual practice? Many units have increased their saturation targets as a result of those studies. This may indeed lead to … Continue reading