Tag Archives: CPAP

Delivering better CPAP in the delivery room, can we avoid intubation in the most immature babies?

Randomized trials have shown that trying to prevent intubation in the DR leads to less severe lung injury. The Cochrane review of prophylactic CPAP compared to immediate intubation included 3 trials (SUPPORT, COIN and DR Management study), that review found … Continue reading

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High-flow in non-tertiary neonatal units: Hunting for answers. #EBNEO

I think Brett Manley is going for the record as the person with the highest proportion of his publications in the FPNEJM, he now has 3, with 2 of them as first author. This is the HUNTER trial where babies … Continue reading

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Under Pressure…

This post “under pressure” isn’t about the classic collaboration between David Bowie and Queen at Live Aid, rather it is about how to wean CPAP. Should we trial preterm babies off for a period every day, or either progressively reduce … Continue reading

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PAS 2018 No7: Protecting tiny noses

#NeoEBM My blog posts are automatically tweeted. A group of twitterers got together at PAS and suggested that this hashtag should become a marker of neonatal Evidence Based Medicine posts. Great initiative! Now I have to find out how to … Continue reading

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PAS 2018 No6: Brett, the HUNTER

Brett Manley from Melbourne is now the person in the world with the greatest trial experience in the use of high flow nasal cannulae in the newborn. He has been the HIPSTER, and is now the HUNTER, I can’t find … Continue reading

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Cannulae for CPAP and nasal ventilation

Mukerji A, Belik J. Neonatal nasal intermittent positive pressure ventilation efficacy and lung pressure transmission. J Perinatol. 2015. This is a lung model study, in which the authors compared the pressure transmission and CO2 elimination effects of nasal IPPV with … Continue reading

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What’s new with Caffeine?

Lodha A, et al. Association of Early Caffeine Administration and Neonatal Outcomes in Very Preterm Neonates. JAMA Pediatr. 2014. First, a study of which I was a co-author; we examined from the CNN whether infants that received caffeine starting in … Continue reading

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Bubble Up

In recent years the introduction of Helping Babies Breathe in low-income countries has proven to be effective in reducing fresh stillbirth rates. Babies who would otherwise be considered to be fresh stillbirths are given a chance, helped to breathe and … Continue reading

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What’s new in non-invasive respiratory support?

A round-up of a few publications that have appeared over the last few months. Lampland AL et al: Bi-level CPAP does not improve gas exchange when compared with conventional CPAP for the treatment of neonates recovering from respiratory distress syndrome. … Continue reading

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High Flow Nasal Cannulae: poor man’s CPAP?

The title is how I sometimes refer to HFNC, but one could ask whether that is all there is to high flow, is it just another way to deliver CPAP, but with no control, or knowledge, of the pressure delivered? … Continue reading

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