Tag Archives: intracranial hemorrhage

Do Sub-Ependymal Haemorrhages cause cerebral palsy?

Posted on 15 December 2020 by keithbarrington

The germinal matrix is a region in the immature brain where a large proportion of cortical neurones are formed before they migrate out to form the neo-cortex. It is intensely metabolically active as it is producing hundreds of thousands of … Continue reading →

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ELVIS is alive!

Posted on 17 August 2020 by keithbarrington

I was searching through the lyrics of ELVIS songs for a quote that might be more apt for this new blog post than “It’s now or ever”, which I have used previously, when I realized that I am a loser, … Continue reading →

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International variations in outcomes of extreme preterm infants

Posted on 9 December 2019 by keithbarrington

A publication from an international collaboration of neonatal databases has just appeared, (Lui K, et al. Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries. J Pediatr. 2019). It makes very interesting … Continue reading →

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Heads up?

Posted on 1 November 2018 by keithbarrington

A new RCT published in the Journal of Perinatology suggests that a midline head position with head elevated at 30 degrees might reduce severe intracranial hemorrhage. (Kochan M, et al. Elevated midline head positioning of extremely low birth weight infants: … Continue reading →

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Its now or… later? A good question to ask ELVIS.

Posted on 19 April 2018 by keithbarrington

This study probably wins the prize for the best trial name in neonatal history, the Early or Late Ventricular Intervention Study, ELVIS. de Vries LS, et al. Treatment thresholds for intervention in posthaemorrhagic ventricular dilation: a randomised controlled trial. Archives … Continue reading →

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Time to abandon the Papile classification? (part 2)

Posted on 7 December 2017 by keithbarrington

As I mentioned in the last post, the initial report of outcomes by Bassan and others showed that the infants with severity score 0, (unilateral haemorrhage without midline shift affecting one zone) had reasonably good outcomes, 7 of 8 had … Continue reading →

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The end of the Papile classification? (part 1)

Posted on 28 November 2017 by keithbarrington

In 1978 Lu-Ann Papile published a landmark article detailing the incidence of intraventricular hemorrhage (IVH) in 46 VLBW preterm infants using CT scanning, describing the differing extent of hemorrhage that may be seen, and developing a grading system (there are … Continue reading →

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New insights on intraventricular haemorrhage

Posted on 19 June 2017 by keithbarrington

A fascinating new study has been published (Tortora D, et al. Differences in subependymal vein anatomy may predispose preterm infants to GMH–IVH. Archives of Disease in Childhood – Fetal and Neonatal Edition. 2017) looking at cerebral venous anatomy as shown … Continue reading →

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Under Pressure….

Posted on 26 August 2015 by keithbarrington

Colm O’Donnell once wrote an article with a whole line from a David Bowie song embedded in the article’s title (O’Donnell CPF. Turn and face the strange – ch..ch..ch..changes to neonatal resuscitation guidelines in the past decade. Journal of Paediatrics … Continue reading →

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Delayed cord clamping or cord milking for the very preterm newborn… or both?

Posted on 18 May 2015 by keithbarrington

What should we be doing, given the current state of the evidence, for the very preterm neonate? I think the evidence is now pretty clear that full-term babies have benefits, and no significant harm, from delayed cord clamping, which has … Continue reading →

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