Monthly Archives: February 2019

How should we evaluate heart rate during neonatal resuscitation?

Many babies receive some sort of “resuscitation” during their transition from intra-uterine to extra-uterine life. How do we decide when a baby needs intervention? A baby who is active and breathing is usually left alone, a baby who is neither … Continue reading

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Death or oxygen, which is worse?

We have a big problem in neonatal research. We have constructed composite outcomes that have become the “standard of design”, but are not of much use for anyone. Because we are, rightly, concerned that death and other diagnoses may be … Continue reading

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Clinical evaluation vs Technology

Two recent trials in adult ICU patients ask very interesting questions, questions which are only linked by testing something clinically simple versus a more technologically demanding evaluation. The first was comparing the use of serum lactate concentrations versus capillary filling … Continue reading

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Fortification of breast milk, Why? When? With What?

The above title is the title of a talk I just gave at the NEO2019 conference. I have made available a .ppt file of the final slides from the talk, under the tab at the top of the page “presentations”. … Continue reading

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…but Oxygen is toxic!

So what about the idea of trials examining even higher oxygen saturations? Is there a chance we might further reduce mortality by aiming for saturations in the mid-90’s rather than the low 90’s? Not so fast, even for adults that … Continue reading

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Oxygen is essential for life……

Aiming for slightly higher oxygen saturation targets (low 90s) decreases mortality in the very preterm neonate (compared to the high 80s), and decreases surgical necrotizing enterocolitis, while increasing retinopathy, and the need for retinopathy treatment, in the long term there … Continue reading

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What now for Lactoferrin?

After a long break over Christmas, New Year and several periods of clinical service, I have a few posts that I am developing, hopefully you will all find them useful. Lactoferrin is a molecule present in mammalian milk which acts … Continue reading

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