Monthly Archives: December 2019

Oropharyngeal airways for resuscitation of the preterm? Throw them away!

Posted on 18 December 2019 by Keith Barrington

When I saw the title of this new study I thought immediately this has to either be by Peter Davis or one or more of his disciples… former trainees, I mean. In fact it is both: Kamlin COF, et al. … Continue reading →

Posted in Neonatal Research | Tagged , | 1 Comment

Oxygen for resuscitation of the very preterm

Posted on 17 December 2019 by Keith Barrington

One of the paradoxes of neonatal respiratory control physiology is that hypoxia depresses respiration whilst hyperoxia stimulates breathing efforts. In fact it’s not such a paradox, prolonged hypoxia in adults decreases respiratory drive also. But could this be relevant in … Continue reading →

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Therapeutic Hypothermia post cardiac arrest

Posted on 13 December 2019 by Keith Barrington

This is a bit off-topic for this blog, but many of you will know that cooling is now used for many other patients than just our full-term asphyxias. Adults who remain with depressed levels of consciousness after resuscitation from a … Continue reading →

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International variations in outcomes of extreme preterm infants

Posted on 9 December 2019 by Keith Barrington

A publication from an international collaboration of neonatal databases has just appeared, (Lui K, et al. Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries. J Pediatr. 2019). It makes very interesting … Continue reading →

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Platelet transfusion threshholds: 25,000 even for the highest risk infants?

Posted on 6 December 2019 by Keith Barrington

The Planet-2 trial that I posted about when it first came out showed no benefit among preterm infants, <34 weeks gestation when they received platelet transfusions at a threshold of 50,00 compared to waiting until they dropped to 25,000. I … Continue reading →

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Diazoxide for hyperinsulinism? Not so fast

Posted on 5 December 2019 by Keith Barrington

Infants with congential persistent hyperinsulinism have been treated for years with diazoxide, well before many of the genetic mutations underlying the condition were known (there are now at least 14 of them!). Diazoxide seems to be relatively well tolerated in … Continue reading →

Posted in Neonatal Research | Tagged | 1 Comment