-
Recent Posts
- Does inhaling Nitric Oxide cause cancer?
- Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM
- Even more thoughts on breast milk fortification
- More on breast milk fortification
- Don’t push so hard! Diaphragmatic hernia babies have fragile lungs that can easily be overdistended.
Respire, bébé, respire!
- Analgesia
- anemia
- antibiotics
- Apnea
- asphyxia
- Assisted Reproduction
- Assisted ventilation
- BPD
- Breast-feeding
- breast milk
- caffeine
- CMV
- Conflicts of Interest
- Congenital Heart Disease
- Convulsions
- CPAP
- Delayed Cord Clamping
- diaphragmatic hernia
- ECMO
- education
- EEG
- Electrolyte therapy
- End-of-life decisions
- endotracheal intubation
- enteral feeding
- Ethics
- extubation
- families
- Fluids
- Gastro-oesophageal reflux
- Global Neonatal Health
- Handicap
- Head Ultrasound
- Health Care Organization
- Heart Surgery
- Hemodynamics
- Hyperglycemia
- Hypoglycemia
- Hypotension
- Hypothermia
- infection control
- intracranial hemorrhage
- iron
- Lactoferrin
- long term outcomes
- lung compliance
- microbiome
- mortality
- MRI
- Necrotising Enterocolitis
- Nitric Oxide
- nutrition
- Obstetrics
- oxygen therapy
- oxygen toxicity
- pain
- PDA
- Prebiotics
- Preventing Prematurity
- Probiotics
- pulmonary physiology
- Quality Improvement
- Randomized Controlled Trials
- Research Design
- Respiratory Management
- Resuscitation
- Retinopathy of Prematurity
- Sepsis
- steroids
- sucrose
- surfactant treatment
- Systematic Reviews
- transfusion
- trisomy
- twins
RSS Links
The Hip Trial: Hypotension in the Preterm
Canadian Premature Babies Foundation
Transport Néonatal
Sainte Justine Hospital
Canadian Neonatal Network
Préma-Québec
La Fondation Sandra Schmirler Foundation
Les Soins du Développement
Categories
Archives
- June 2018
- May 2018
- April 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- December 2015
- November 2015
- October 2015
- September 2015
- August 2015
- June 2015
- May 2015
- April 2015
- March 2015
- February 2015
- January 2015
- December 2014
- November 2014
- October 2014
- September 2014
- August 2014
- June 2014
- May 2014
- April 2014
- March 2014
- February 2014
- January 2014
- December 2013
- November 2013
- October 2013
- September 2013
- August 2013
- July 2013
- June 2013
- May 2013
- April 2013
- March 2013
- February 2013
- January 2013
- December 2012
- November 2012
- October 2012
- September 2012
- August 2012
- July 2012
- June 2012
- May 2012
Meta
Tag Archives: Research Design
Reading Research: Subgroups and Observational studies
In publications of randomized controlled trials, subgroup analyses are frequently performed. The idea behind such analyses being to determine whether one group or another has a different result to the overall results, for example, whether boys or girls have more … Continue reading
Two New Publications
After a few weeks break (for a number of reasons), I’m ready to start blogging again! I’m sure you have all missed the succinct and perceptive critiques of the recent neonatal literature, but today I will start with 2 publications … Continue reading
Posted in Neonatal Research
Tagged Ethics, Health Care Organization, mortality, Research Design
Leave a comment
The best outcome variable for very preterm newborns?
Death or ‘neurodevelopmental impairment’ (NDI) as a combined outcome has become a sort of de facto standard as the primary outcome for neonatal clinical trials. Because many very preterm infants have developmental delay, intellectual and learning difficulties, and some have … Continue reading
Conflicts of interest are not all financial, but they are conflicts none the less. Name change not required.
Another poorly argued article trying to minimize the reality of conflicts of interest in medical research. Cappola AR, FitzGerald GA. Confluence, not conflict of interest: Name change necessary. JAMA. 2015;314(17):1791-2. If someone stands to have a personal advantage as a result … Continue reading
Late Surfactant may not be effective, probably.
A large multi-center trial (n=511) led by Roberta Ballard has just been published. (Ballard RA, et al. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide. J Pediatr 2015.) In this trial infants had similar … Continue reading
Posted in Neonatal Research
Tagged BPD, mortality, Randomized Controlled Trials, Research Design, surfactant treatment
Leave a comment
Murky Guidance
After the OHRP meetings and their evaluation of the SUPPORT controversy, the OHRP have now released what they call “Draft Guidance on Disclosing Reasonably Foreseeable Risks in Research Evaluating Standards of Care” The conclusion of the draft guidance starts with … Continue reading
What do parents of twins (and the twins) think about randomizing multiples
There has been some controversy recently about how we should randomize twins (and triplets or more) in neonatal trials. The question being whether randomizing the babies independently or randomizing them as a group is preferable. Those who wish to randomize … Continue reading
Posted in Neonatal Research
Tagged Randomized Controlled Trials, Research Design, twins
Leave a comment
