Category Archives: Neonatal Research

Erythropoietin for brain protection in the very preterm? Not worth Penuts.

That isn’t a mis-spelling, just a bad attempt to play with the acronym for a good trial; the PENUT trial, just published in the (FP)NEJM. (Juul SE, et al. A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants. N … Continue reading

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Gene therapy for SMA; who will win the lottery?

There are few things more disgusting than the obscene actions of drug companies that profit off the distress of dying babies and their families. You might think that the price of a drug would be based on development and production … Continue reading

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Oropharyngeal airways for resuscitation of the preterm? Throw them away!

When I saw the title of this new study I thought immediately this has to either be by Peter Davis or one or more of his disciples… former trainees, I mean. In fact it is both: Kamlin COF, et al. … Continue reading

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Oxygen for resuscitation of the very preterm

One of the paradoxes of neonatal respiratory control physiology is that hypoxia depresses respiration whilst hyperoxia stimulates breathing efforts. In fact it’s not such a paradox, prolonged hypoxia in adults decreases respiratory drive also. But could this be relevant in … Continue reading

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Therapeutic Hypothermia post cardiac arrest

This is a bit off-topic for this blog, but many of you will know that cooling is now used for many other patients than just our full-term asphyxias. Adults who remain with depressed levels of consciousness after resuscitation from a … Continue reading

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International variations in outcomes of extreme preterm infants

A publication from an international collaboration of neonatal databases has just appeared, (Lui K, et al. Trends in Outcomes for Neonates Born Very Preterm and Very Low Birth Weight in 11 High-Income Countries. J Pediatr. 2019). It makes very interesting … Continue reading

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Platelet transfusion threshholds: 25,000 even for the highest risk infants?

The Planet-2 trial that I posted about when it first came out showed no benefit among preterm infants, <34 weeks gestation when they received platelet transfusions at a threshold of 50,00 compared to waiting until they dropped to 25,000. I … Continue reading

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