-
Recent Posts
breathe, baby, breathe
- Analgesia
- anemia
- antibiotics
- Apnea
- asphyxia
- Assisted ventilation
- BPD
- Breast-feeding
- breast milk
- Conflicts of Interest
- Congenital Heart Disease
- Convulsions
- Cost effectiveness
- CPAP
- Delayed Cord Clamping
- ECMO
- EEG
- End-of-life decisions
- endotracheal intubation
- enteral feeding
- erythropoietin
- Ethics
- extubation
- families
- Fluids
- Gastro-oesophageal reflux
- Global Neonatal Health
- Handicap
- Head Ultrasound
- Health Care Organization
- Heart Surgery
- Hemodynamics
- Hyperglycemia
- Hypoglycemia
- Hypotension
- Hypothermia
- hypoxic ischemic encephalopathy
- infection control
- intracranial hemorrhage
- Lactoferrin
- long term outcomes
- lung compliance
- microbiome
- mortality
- MRI
- Necrotising Enterocolitis
- Nitric Oxide
- nutrition
- Obstetrics
- oxygen therapy
- oxygen toxicity
- pain
- PDA
- Prebiotics
- Preventing Prematurity
- Probiotics
- pulmonary physiology
- Quality Improvement
- quality of life
- Randomized Controlled Trials
- Research Design
- Respiratory Management
- respiratory support
- Resuscitation
- Retinopathy of Prematurity
- RSV
- Sepsis
- statistics
- steroids
- sucrose
- surfactant treatment
- Systematic Reviews
- transfusion
- trisomy
- twins
Respire, bébé, respire!
RSS Links
Canadian Premature Babies Foundation
Sainte Justine Hospital
Canadian Neonatal Network
Préma-Québec
Categories
Transport Néonatal
Archives
- January 2021
- December 2020
- October 2020
- September 2020
- August 2020
- July 2020
- May 2020
- April 2020
- March 2020
- February 2020
- January 2020
- December 2019
- November 2019
- October 2019
- September 2019
- June 2019
- May 2019
- April 2019
- March 2019
- February 2019
- December 2018
- November 2018
- October 2018
- June 2018
- May 2018
- April 2018
- February 2018
- January 2018
- December 2017
- November 2017
- October 2017
- September 2017
- August 2017
- July 2017
- June 2017
- May 2017
- April 2017
- March 2017
- February 2017
- January 2017
- December 2016
- November 2016
- October 2016
- September 2016
- August 2016
- June 2016
- May 2016
- April 2016
- March 2016
- February 2016
- January 2016
- December 2015
- November 2015
- October 2015
- September 2015
- August 2015
- June 2015
- May 2015
- April 2015
- March 2015
- February 2015
- January 2015
- December 2014
- November 2014
- October 2014
- September 2014
- August 2014
- June 2014
- May 2014
- April 2014
- March 2014
- February 2014
- January 2014
- December 2013
- November 2013
- October 2013
- September 2013
- August 2013
- July 2013
- June 2013
- May 2013
- April 2013
- March 2013
- February 2013
- January 2013
- December 2012
- November 2012
- October 2012
- September 2012
- August 2012
- July 2012
- June 2012
- May 2012
Meta
Category Archives: Neonatal Research
More about Prebiotics
I don’t know if there is an “official” definition of prebiotics, but I think of them as molecules present in the diet that promote the growth of probiotic organisms. I believe that originally the term was applied only to molecules … Continue reading
Posted in Neonatal Research
Tagged Necrotising Enterocolitis, Prebiotics, Probiotics, Systematic Reviews
Leave a comment
When should we transfuse preterm babies, and why? Redux.
The TOP trial has just been published in the FPNEJM (Kirpalani H, et al. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. N Engl J Med. 2020;383(27):2639-51). It was a multicenter, non-masked RCT among 1800 babies of less than … Continue reading
Posted in Neonatal Research
Tagged anemia, long term outcomes, Randomized Controlled Trials, transfusion
1 Comment
Should all asphyxiated babies have MR spectroscopy?
MRI post-asphyxia, and post-rewarming, seems to be more predictive of long term outcomes than MRI at term for preterm infants. Imaging and analysis of the Apparent Diffusion Coefficient in the PLIC (posterior Limb of the Internal Capsule), for example, has … Continue reading
Posted in Neonatal Research
Tagged hypoxic ischemic encephalopathy, long term outcomes
Leave a comment
Do Sub-Ependymal Haemorrhages cause cerebral palsy?
The germinal matrix is a region in the immature brain where a large proportion of cortical neurones are formed before they migrate out to form the neo-cortex. It is intensely metabolically active as it is producing hundreds of thousands of … Continue reading
Posted in Neonatal Research
Tagged cerebral palsy, intracranial hemorrhage, long term outcomes
Leave a comment
Does intravitreal bevacizumab adversely affect long term development? Two simultaneous systematic reviews say yes, or no.
A reliable answer to the above question would require a large multicentre RCT comparing intravitreal bevacizumab (IVB) to laser, powered for long term outcomes. Such a trial does not currently exist. As a result, 2 groups have just published systematic … Continue reading
Posted in Neonatal Research
Tagged long term outcomes, Retinopathy of Prematurity, Systematic Reviews
4 Comments
Three trials with null results, how should we respond?
These 3 articles have just been published, all show no difference in long term outcomes between the randomized groups. What does that mean for the impact on therapeutic decision-making? Natalucci G, et al. Neurodevelopmental Outcomes at Age 5 Years After … Continue reading
What role for High Flow Nasal Cannulae?
There are a few new publications which might help us to answer the question posed in the title of this post. When heated, humidified, high flow nasal cannulae were first being spoken about I remembered an old study using standard … Continue reading
Posted in Neonatal Research
Tagged BPD, Randomized Controlled Trials, respiratory support
3 Comments
Probiotics and NEC, the latest answer?
The updated Cochrane review of probiotics for prevention of NEC, sepsis and mortality has been published. Meta-analysis showed that probiotics may reduce the risk of NEC: RR 0.54, 95% CI 0.45 to 0.65 (54 trials, 10,604 infants; I2 = 17%); … Continue reading
Quality of life cannot be predicted from a brain scan
…either ultrasound or MRI, or by EEG, or neurological examination, or even during follow-up by screening for disabilities. That title is from a recently published editorial (Fayed N, et al. Quality of life cannot be predicted from a brain scan. … Continue reading
Posted in Neonatal Research
Tagged Head Ultrasound, long term outcomes, MRI, quality of life
1 Comment