Category Archives: Neonatal Research

“The war to end all wars” 100 years on

Among the many moving ceremonies to mark the centenary of the Armistice, a series of portraits of casualties of the first world war were stencilled in the sand around Britain, the project is called “Pages of the Sea”, which is … Continue reading

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Under Pressure…

This post “under pressure” isn’t about the classic collaboration between David Bowie and Queen at Live Aid, rather it is about how to wean CPAP. Should we trial preterm babies off for a period every day, or either progressively reduce … Continue reading

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More about platelets

The recent RCT comparing transfusion thresholds of 25,000 per mm3 to 50,000 in very preterm babies has generated a great deal of discussion. The result was somewhat unexpected, I think. I would not have been surprised to find that there … Continue reading

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Platelet transfusions don’t prevent bleeding (and may increase mortality).

When do you give a platelet transfusion? You could easily ask 10 different neonatologists and get 15 different answers. I would be one of those who gave several different answers depending on the clinical situation, believing that thrombocytopenia of different … Continue reading

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Heads up?

A new RCT published in the Journal of Perinatology suggests that a midline head position with head elevated at 30 degrees might reduce severe intracranial hemorrhage. (Kochan M, et al. Elevated midline head positioning of extremely low birth weight infants: … Continue reading

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Active intervention at 22 weeks gestation, is it futile?

In order to respond to the question posed in the title we need first to agree on what “futile” means. It could mean “it never works” or, “it can work but the ultimate result is so bad that it isn’t … Continue reading

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Prebiotics and preterms and probiotics.

A selection of recent publications, regarding the issues in the title, that I find interesting and which seem to tell a consistent story. From Nick Embleton’s group the following interesting study (Stewart CJ, et al. Longitudinal development of the gut … Continue reading

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