Tag Archives: BPD

Automated oxygen control, what’s taking so long?

A long long time ago, in a galaxy… actually quite near here, the idea of servo control of inspired oxygen was already in the air. At the time I first heard about it, the idea was to control FiO2 based … Continue reading

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Preterm babies, PLEASE don’t smoke!

One of the most addictive and harmful drugs of all is perfectly legal. Tobacco, and the nicotine it contains, are subject to prohibition for adults nowhere in the world, despite millions of deaths, prolonged severe disability, and being probably as … Continue reading

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Steroids to improve pulmonary outcomes in preterm infants.

When we consider using steroids in a preterm infant, ventilator dependent, with evolving lung disease, what outcomes are we most interested in? Survival, surely, is the first outcome that we want to improve, and secondly long-term pulmonary health. The adverse … Continue reading

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Hydrocortisone, with backup dexamethasone, to prevent Bronchopulmonary Dysplasia

A trial that has been awaited for a while has just been published (Watterberg KL, et al. Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia. N Engl J Med. 2022;386(12):1121-31). It was a multi-centre RCT of hydrocortisone in 800 very preterm … Continue reading

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Does Gastro-Oesophageal Reflux matter in BronchoPulmonary Dysplasia?

The title is deliberately a bit vague as I wanted to discuss whether GOR contributes to the pathogenesis of BPD, and also whether it is important in infants with established BPD. Does GOR contribute to the development of BPD? There … Continue reading

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Survival and outcomes for the extremely preterm. The NICHD network results continue to improve: Can we do even better?

A new publication from the NRN describes short term outcomes and care practices of babies from 22 to 28 weeks gestation born in recent years (2013 to 2018) and for those born in 2013-2016 results of evaluations of those followed … Continue reading

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STOP-BPD follow up study

Does routine hydrocortisone, started at 7 to 14 days of age among infants <30 weeks GA and/or <1250g birth weight who were ventilator dependent and at increased risk for BPD, affect their long term developmental progress? (Halbmeijer NM, et al. … Continue reading

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Was OPTIMIST too optimistic?

One of the trials we have been waiting for has just been published Dargaville PA, et al. Effect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A … Continue reading

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Neonatal Updates

It’s a long time since I did one of these, but there were several publications that I thought warranted a quick comment. Abbey NV, et al. Electrocardiogram for heart rate evaluation during preterm resuscitation at birth: a randomized trial. Pediatr … Continue reading

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What role for High Flow Nasal Cannulae?

There are a few new publications which might help us to answer the question posed in the title of this post. When heated, humidified, high flow nasal cannulae were first being spoken about I remembered an old study using standard … Continue reading

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