Tag Archives: BPD

Causes and Consequences of Bronchopulmonary Dysplasia

Sullivan K, et al. The Association between Positive Tracheal Aspirate Cultures and Adverse Pulmonary Outcomes in Preterm Infants with Severe Bronchopulmonary Dysplasia. American journal of perinatology. 2016(EFirst).  This is an interesting study, with many limitations. 121 intubated VLBW preterm infants … Continue reading

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Caffeine protects the lungs

From the CAP trial we know that caffeine administration leads to less bronchopulmonary dysplasia. The question is how? The mechanism could help to design other studies, or help in a decision about clinical use where the question hasn’t been directly … Continue reading

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How to define BPD

An article published at the end of 2015, (I only just got the full-text) compared 3 diagnostic criteria for defining BPD. The original 36 week threshold by Andy Shennan, the NIH workshop definition, and the ‘physiologic’ definition requiring a room-air … Continue reading

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CMV transmission by breast milk in the very preterm, how important is it?

Over the past couple of years there have been quite a few articles addressing this issue, so I guess it must be important. The results of all these studies are not consistent, however, Kelly MS, et al. Postnatal Cytomegalovirus Infection … Continue reading

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Which Surfactant is best?

Singh N, et al. Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants. Cochrane database of systematic reviews (Online). 2015;12:CD010249. This is the sort of systematic review that I find really helpful. Some … Continue reading

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Follow up of the PREMILOC post

Further to my post about the PREMILOC trial of routine hydrocortisone supplementation in extremely preterm infants, I received an email response from Olivier Baud, who was generally in agreement with my comments, but doubts the validity of adding the data … Continue reading

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Inhaled steroids to prevent BPD, another trial.

This time from Japan, Nakamura T, et al. Early inhaled steroid use in extremely low birthweight infants: a randomised controlled trial. Archives of Disease in Childhood – Fetal and Neonatal Edition. 2016. 211 babies with a birth weight less than 1000 … Continue reading

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