Tag Archives: BPD

At last, something men are better at than women!

That is, giving blood for babies, at least maybe. The introduction to this new publication notes something that I was not aware of, that plasma donated by women is associated with a substantially greater frequency of transfusion related complications than … Continue reading

Posted in Neonatal Research | Tagged , | 1 Comment

PAS 2018 No2: let’s STOP-BPD

The STOP-BPD trial was a multicenter trial from Holland, (registered as NTR2768) over 180 babies were randomized to each arm of this trial, they were <30 weeks or less than 1250 g at birth, and were still ventilated at 2 … Continue reading

Posted in Neonatal Research | Tagged , , | Leave a comment

Inhaled Steroids to Prevent BPD? Think again… again!

The NEUROSIS trial that I discussed in my previous post has, among other published trials, most in common with the trial by Nakamura published in 2016. Nakamura T, et al. Early inhaled steroid use in extremely low birthweight infants: a … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Early low dose hydrocortisone seems to not affect medium term development; PREMILOC outcomes at 22 months.

The PREMILOC trial was a multi-center RCT of hydrocortisone, 0.5mg/kg twice per day for 7 days followed by 0.5 mg/kg per day for 3 days, given starting within 24 hours of age to infants of 24 to less than 28 … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Fluid restriction to prevent BPD?

In response to my previous post, one of the comments was a question about fluid volumes in the first few days of life, and whether fluid and/or sodium intake was important for the development of BPD during the early neonatal … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Fluid restriction as treatment for BPD? This time with the summary of findings table.

I realize that many of my gentle readers may not have access to the Cochrane reviews in full text as soon as they are published. The NICHD do provide free access to the neonatal reviews, (together with a useful introduction … Continue reading

Posted in Neonatal Research | Tagged , , , | 2 Comments

New Publication: Does fluid restriction improve the clinical status of babies with BPD?

I have never been convinced that fluid restriction is a good thing for kids with BPD. I think the common practice came about because of the short-term improvements in lung function that sometimes follow if you start diuretics. The idea … Continue reading

Posted in Neonatal Research | Tagged , , , | 2 Comments