Tag Archives: oxygen toxicity

Too much oxygen is bad for adults too!

The systematic review of the neonatal oxygen saturation targeting trials Askie LM, et al. Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants. Cochrane database of systematic reviews (Online). 2017;4:Cd011190. confirmed the increase … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Still more doubts about BOOSTing saturations?

I won’t make a point-by-point response to Reese’s comments, mostly because I agree with most of them! Oxygen is toxic. Minimizing oxygen toxicity is a vitally important issue. Alarm fatigue is a major problem. In our NICU we performed an … Continue reading

Posted in Neonatal Research | Tagged , , , , | 1 Comment

More Doubts about BOOSTing saturations?

As I just mentioned I received another thoughtful comment from Reese Clark, which I reproduce in its entirety below: “After re-reading my post and at the risk of being a bit redundant with what Dr Barrington has already carefully presented … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment

Doubts about BOOSTING saturations?

I received a very thoughtful comment from Reese Clark, who many of you will know as a leader in neonatology whose many years of experience and important scientific contributions to neonatology make him someone worth listening to. He has doubts … Continue reading

Posted in Neonatal Research | Tagged , , , | 3 Comments

Retinopathy: up or down?

The oxygen saturation targeting trials showed more retinopathy with higher oxygen saturation targets. Will this translate into more retinopathy in actual practice? Many units have increased their saturation targets as a result of those studies. This may indeed lead to … Continue reading

Posted in Neonatal Research | Tagged , , | 3 Comments

Lower oxygen resuscitation for preterms?

A new publication from a group of us in the CNN, suggests that the answer to that query is ‘not so fast’. Rabi Y, Lodha A, Soraisham A, Singhal N, Barrington K, Shah PS, et al. Outcomes of preterm infants following … Continue reading

Posted in Neonatal Research | Tagged , , , | 4 Comments

Oxygen is good for you

Of course you can have too much of a good thing, but you should also try and stay above the minimum. The COT trial investigators, led by Christian Poets, have published a secondary analysis of the results, examining in particular … Continue reading

Posted in Neonatal Research | Tagged , , , , | Leave a comment