Tag Archives: Nitric Oxide

Does inhaling Nitric Oxide cause cancer?

Posted on 21 June 2018 by keithbarrington

How would you answer the question posed in this title? Given the relative rarity of infant cancers, I guess you would have to follow thousands of babies treated with iNO, and compare with thousands of babies who were equally sick … Continue reading →

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Happy New Review no. 2; Inhaled NO in the full term infant

Posted on 17 January 2017 by keithbarrington

We have also updated the Cochrane review of inhaled NO in the term infant. (Barrington KJ, Finer N, Pennaforte T, Altit G. Nitric oxide for respiratory failure in infants born at or near term. Cochrane database of systematic reviews (Online). … Continue reading →

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Happy New Year! And Happy Reading; an update of the Cochrane review: nitric oxide in the preterm

Posted on 13 January 2017 by keithbarrington

A major revision of the Cochrane review of inhaled nitric oxide gas in the preterm infant is now available. (Barrington KJ, Finer N, Pennaforte T. Inhaled nitric oxide for respiratory failure in preterm infants. Cochrane database of systematic reviews (Online). … Continue reading →

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Off-label NO: No… or Yes?

Posted on 8 April 2015 by keithbarrington

Recent articles about off-label use of inhaled Nitric Oxide (iNO) in the preterm infant shows that such use is : a. extremely variable from one center to another, (Truog WE, et al. Inhaled nitric oxide usage in preterm infants in … Continue reading →

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NO, not diaphragmatic Hernias!

Posted on 8 September 2014 by keithbarrington

Many of you will know that I am responsible for the inhaled NO systematic review in the Cochrane database.  One part of that review examines the data for iNO use in infants with diaphragmatic hernia. Unfortunately there were only about … Continue reading →

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Inhaled Nitric Oxide in Preterms

Posted on 18 August 2014 by keithbarrington

Kinsella JP, Cutter GR, Steinhorn RH, Nelin LD, Walsh WF, Finer NN, et al. Noninvasive Inhaled Nitric Oxide Does Not Prevent Bronchopulmonary Dysplasia in Premature Newborns. The Journal of pediatrics. 2014. My Cochrane review (which is in the process of being … Continue reading →

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Pluto, not just a planet anymore.

Posted on 11 September 2013 by keithbarrington

Or should that be, not even a planet… One other thing I wanted to mention about the PLUTO trial is the entry criterion. The main entry criterion was the presence of clear lower urinary tract obstruction in a male fetus, … Continue reading →

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