Tag Archives: microbiome

Quoted in “nature”

Posted on 5 April 2018 by

An interesting and well-written article in nature (or, at least, a supplement called “nature outlook”) by a scientific journalist Sarah DeWeerdt has appeared, discussing the acquisition of the intestinal microbiome by newborn infants. She discusses premature infants and the role … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Necrotizing Enterocolitis: manipulating the microbiome, part 3

Posted on 9 May 2016 by

Abdulkadir B, et al. Stool bacterial load in preterm infants with necrotising enterocolitis. Early Hum Dev. 2016;95:1-2.  More work from the Newcastle group, this time the group decided not to look at the proportion of different bugs in the stools, … Continue reading →

Posted in Neonatal Research | Tagged , , , , | 2 Comments

Necrotizing Enterocolitis: manipulating the microbiome, part 2

Posted on 6 May 2016 by

The Newcastle, UK, group has published an article about the intestinal microbiome of babies receiving routine probiotic prophylaxis. Abdulkadir B, et al. Routine Use of Probiotics in Preterm Infants: Longitudinal Impact on the Microbiome and Metabolome. Neonatology. 2016;109(4):239-47. The authors studied 7 … Continue reading →

Posted in Neonatal Research | Tagged , | 2 Comments

Necrotizing Enterocolitis: manipulating the microbiome, part 1

Posted on 6 May 2016 by

Some very interesting recent publications about NEC, so I will post a multi-part bumper posting. The first has just been published (in tomorrow’s Lancet) Warner BB, et al. Gut bacteria dysbiosis and necrotising enterocolitis in very low birthweight infants: a prospective … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment

Prebiotics, Probiotics and the microbiome

Posted on 2 October 2015 by

A series of interesting recent articles: Yang J, et al. Application of Laser Capture Microdissection and 16S rRNA Gene Polymerase Chain Reaction in the Analysis of Bacteria Colonizing the Intestinal Tissue of Neonates With Necrotizing Enterocolitis. Pediatr Infect Dis J. … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Frozen poop sounds much more palatable

Posted on 7 November 2014 by

Fecal transplants are effective in treatment of persistent clostridium difficile infections. The publication showing that, in the small RCT published in the PNEJM, was remarkable in the pre-screened donors who were ready and available to produce a “donation” on demand. … Continue reading →

Posted in Neonatal Research | Tagged | Leave a comment

Stop the Antibiotics!

Posted on 21 February 2014 by

We know that prolonged antibiotic use in preterm babies increase their chance of later developing NEC. The assumption being that the disturbance of the intestinal flora leads to the increase in susceptibility. Here is some more direct evidence to support … Continue reading →

Posted in Neonatal Research | Tagged , , | 4 Comments