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Meta
Tag Archives: long term outcomes
We need to rethink neonatal hypoglycaemia
A great deal of time and effort is expended to detect and treat low blood sugars in the newborn. Studies to determine risk factors, monitoring schedules, and treatment strategies have taken a great deal of effort, and implementing the recommended … Continue reading
Steroids to improve pulmonary outcomes in preterm infants.
When we consider using steroids in a preterm infant, ventilator dependent, with evolving lung disease, what outcomes are we most interested in? Survival, surely, is the first outcome that we want to improve, and secondly long-term pulmonary health. The adverse … Continue reading
Posted in Neonatal Research
Tagged BPD, long term outcomes, Randomized Controlled Trials
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Dexmedetomidine: new wonder drug or next neonatal disaster?
In many units, including my own, dexmedetomidine (DXM) has been creeping into use. Initially, we noticed in some full term babies who returned from the operating room, the medication appeared in the anaesthesia record, then when infants returned occasionally with … Continue reading
What do we tell families at 22 weeks?
When we counsel families about the potential outcomes for infants born profoundly preterm, I think we would all agree that we should be honest, transparent and truthful. Which includes, I would suggest, truthfulness about our own local results, as well … Continue reading
Speak French to your babies (or Chinese) in the NICU
This is a fascinating study from Columbus Ohio in mildly preterm babies when they reached term. (Richard C, et al. Randomized Trial to Increase Speech Sound Differentiation in Infants Born Preterm. J Pediatr. 2021) We know that prematurity and NICU … Continue reading
Survival and longer term outcomes for the extremely preterm. The NICHD network results.
In addition to the short term results that I just posted about, the publication from the NICHD NRN describes the longer term outcomes of the babies of 22 to 26 weeks GA born between 2013-2016 who completed their 2 year … Continue reading
STOP-BPD follow up study
Does routine hydrocortisone, started at 7 to 14 days of age among infants <30 weeks GA and/or <1250g birth weight who were ventilator dependent and at increased risk for BPD, affect their long term developmental progress? (Halbmeijer NM, et al. … Continue reading
Posted in Neonatal Research
Tagged BPD, long term outcomes, Randomized Controlled Trials, steroids
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How do we make decisions for the most immature babies, with their families?
Although babies under 25 weeks account for a tiny proportion of births, and a small proportion of NICU admissions, the importance of the question asked in the title can be seen by the ongoing number of publications, below are just … Continue reading
Posted in Neonatal Research
Tagged End-of-life decisions, Ethics, long term outcomes, periviable delivery, Resuscitation
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Should we treat electrographic seizures?
In order to answer the question posed in the title you would need to take babies at risk of seizures, but not yet having clinically diagnosed convulsions, randomize them to have routine continuous EEG monitoring or not and then treat … Continue reading
Posted in Neonatal Research
Tagged anticonvulsants, Convulsions, long term outcomes, Randomized Controlled Trials
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Intestinal perforation in the very preterm, what causes it, and what to do about it.
There are 2 main causes of intestinal perforation in the very preterm, Necrotising Enterocolitis and Spontaneous Perforation. NEC, as I have previously discussed, may be a convenient name for a few different conditions which present in a similar fashion. In … Continue reading
Neonatal Research 