Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

BOOST-II long term outcomes

Posted on 16 February 2016 by Keith Barrington

The long-running epic of the oxygen saturation targeting trials is nearing completion. This publication of the joint results of the Australia and UK trials now includes the primary outcome for the trials, the combined rate of death or “disability”. Australia … Continue reading →

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Antenatal Steroids at 36 weeks?

Posted on 11 February 2016 by Keith Barrington

Most of the studies of antenatal steroids for lung maturation included mothers at less than 34 weeks. Most babies at 34 to 36 weeks do fine, although there is a growing realization of their increased long term risks. Even the … Continue reading →

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Preventing and Treating Sepsis in Preterm Babies

Posted on 10 February 2016 by Keith Barrington

These two studies are both issues that I am involved with, Theresa Ochoa’s study I was aware of, and was waiting for the full publication, the other, from Egypt, I didn’t know about but should have done, but it confirms … Continue reading →

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Good Advice

Posted on 9 February 2016 by Keith Barrington

Sometime you can find things on the Internet that are better than many medical help sites. Here is advice that can apply to almost anyone with a newborn baby who has a life-changing diagnosis, almost anytime. Always remember this: “A diagnosis … Continue reading →

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Enhanced Nutrition

Posted on 9 February 2016 by Keith Barrington

Strømmen K, et al. Enhanced Nutrient Supply to Very Low Birth Weight Infants is Associated with Improved White Matter Maturation and Head Growth. Neonatology. 2015;107(1):68-75. This is a report of a secondary outcome of a small RCT, there were only … Continue reading →

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Neonatal Updates

Posted on 9 February 2016 by Keith Barrington

Glasson EJ, et al. Improved Survival in Down Syndrome over the Last 60 Years and the Impact of Perinatal Factors in Recent Decades. The Journal of pediatrics. 2016;169:214-20.e1. This is a fascinating study, showing dramatic improvements in the survival of persons … Continue reading →

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Interesting comments

Posted on 9 February 2016 by Keith Barrington

I get a small number of comments on the blog, almost always interesting, depending on how you view the content you may not have noticed them. Three of my recent posts have stimulated some comments that are worthwhile: If you … Continue reading →

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Ventilating infants with Diaphragmatic Hernia

Posted on 6 February 2016 by Keith Barrington

Snoek KG, et al. Conventional Mechanical Ventilation Versus High-frequency Oscillatory Ventilation for Congenital Diaphragmatic Hernia: A Randomized Clinical Trial (The VICI-trial). Ann Surg. 2015. There a few few remarkable things about this study; the first is part of the preamble: Since … Continue reading →

Posted in Neonatal Research | 6 Comments

A New Publication

Posted on 5 February 2016 by Keith Barrington

Janvier A, Farlow B, Barrington KJ. Cardiac surgery for children with trisomies 13 and 18: Where are we now? Seminars in Perinatology. 2016. Annie and Barb and I have just published this review of the current situation regarding cardiac surgery … Continue reading →

Posted in Neonatal Research | 2 Comments

The death knell for Xenon?

Posted on 4 February 2016 by Keith Barrington

Azzopardi D, et al. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial. The Lancet Neurology. 2016;15(2):145-53.  Babies who undergo therapeutic hypothermia for perinatal encephalopathy … Continue reading →

Posted in Neonatal Research | Tagged , | 4 Comments