Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Blood pressures in very immature babies

Posted on 4 May 2016 by Keith Barrington

One recent publication initially looked very interesting from the title, Vesoulis ZA, et al. Empirical estimation of the normative blood pressure in infants <28 weeks gestation using a massive data approach. J Perinatol. 2015. Unfortunately the authors interpretation of ‘massive data’ is … Continue reading →

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Unilateral DNR orders?

Posted on 4 May 2016 by Keith Barrington

A paper from Mark Mercurio and colleagues has been making some waves. In it they address the question of unilateral DNAR orders (previously called Do Not Resuscitate DNR orders, but now often referred to, more accurately as Do Not Attempt … Continue reading →

Posted in Neonatal Research | 3 Comments

New achievements!

Posted on 4 May 2016 by Keith Barrington

Neonatal research has now passed a total of 400,000 page views since it started, thanks to many people for their encouragement My researchgate profile now shows over 5,000 citations of articles I have authored, or co-authored. Sometimes when you publish … Continue reading →

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Death of a twin, further resources.

Posted on 12 April 2016 by Keith Barrington

I recently wrote about the work from Newcastle in the UK about supporting parents who lose one of a pair of twins during the perinatal period. Nick Embleton wrote a comment about that post noting that they now have put … Continue reading →

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Follow up of the PREMILOC post

Posted on 12 April 2016 by Keith Barrington

Further to my post about the PREMILOC trial of routine hydrocortisone supplementation in extremely preterm infants, I received an email response from Olivier Baud, who was generally in agreement with my comments, but doubts the validity of adding the data … Continue reading →

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Inhaled steroids to prevent BPD, another trial.

Posted on 12 April 2016 by Keith Barrington

This time from Japan, Nakamura T, et al. Early inhaled steroid use in extremely low birthweight infants: a randomised controlled trial. Archives of Disease in Childhood – Fetal and Neonatal Edition. 2016. 211 babies with a birth weight less than 1000 … Continue reading →

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Late surfactant supplementation

Posted on 8 April 2016 by Keith Barrington

After the initial phase of surfactant deficiency of the very preterm infant, inhibition and destruction of surfactant are common, the inflammation of the oxygen exposed preterm lung is probably important in the pathophysiology of bronchopulmonary dysplasia, and the adverse effects … Continue reading →

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Death of a twin

Posted on 6 April 2016 by Keith Barrington

Twins are much more likely to end up in the care of the NICU than singletons, and much more likely to be extremely preterm, and as a result the phenomenon of having one of twins die, while the other remains … Continue reading →

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TPN toxic?

Posted on 28 March 2016 by Keith Barrington

Humans, after they are born, are supposed to receive their nutrition via the gut. Before that of course, they receive a continuous infusion of nutrition via the umbilical vein. We are far from having an intravenous nutrition mixture for sick … Continue reading →

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Neonatal Updates

Posted on 15 March 2016 by Keith Barrington

Sehgal A, et al. Systemic arterial stiffness in infants with bronchopulmonary dysplasia: potential cause of systemic hypertension. J Perinatol. 2016. Elevated systemic pressures are common in infants with moderate or severe BPD; why? Dr Sehgal and his colleagues performed vascular ultrasound … Continue reading →

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