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Meta
Tag Archives: Probiotics
Do Probiotics work in the UK?
Seems like a dumb question I know, if they work in one country, surely they should work everywhere? It is sometimes difficult, however, to institute change based on studies that are done elsewhere, usually because there is an idea, or … Continue reading
Prebiotics and preterms and probiotics.
A selection of recent publications, regarding the issues in the title, that I find interesting and which seem to tell a consistent story. From Nick Embleton’s group the following interesting study (Stewart CJ, et al. Longitudinal development of the gut … Continue reading
Posted in Neonatal Research
Tagged breast milk, Necrotising Enterocolitis, Prebiotics, Probiotics, Sepsis
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Probiotics for extremely preterm infants
The use of probiotics for Necrotising enterocolitis prophylaxis in the very preterm is increasing across Canada. There are apparently, though, centers that will only give them to larger preterm infants, and not to the most immature. I think that is … Continue reading
Necrotizing Enterocolitis: manipulating the microbiome, part 3
Abdulkadir B, et al. Stool bacterial load in preterm infants with necrotising enterocolitis. Early Hum Dev. 2016;95:1-2. More work from the Newcastle group, this time the group decided not to look at the proportion of different bugs in the stools, … Continue reading
Prebiotics, Probiotics and the microbiome
A series of interesting recent articles: Yang J, et al. Application of Laser Capture Microdissection and 16S rRNA Gene Polymerase Chain Reaction in the Analysis of Bacteria Colonizing the Intestinal Tissue of Neonates With Necrotizing Enterocolitis. Pediatr Infect Dis J. … Continue reading
Posted in Neonatal Research
Tagged microbiome, Necrotising Enterocolitis, Probiotics
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Genetic variants and NEC risk
This post is out of my usual comfort zone, but I thought I’d write about it as it is fascinating, and might lead to something clinical. I don’t understand any of the lab methodology of this study, except to say … Continue reading
What is the news about probiotics?
A few things have been happening recently: first of all, the big news was that Solgar recalled ABCDophilus as a result of some contamination of the product. As many of you will probably know, there was fungal contamination of the … Continue reading
Posted in Neonatal Research
Tagged Necrotising Enterocolitis, Probiotics, Randomized Controlled Trials
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Responses to letters regarding our Journal of Pediatrics Probiotics article
Here are my answers to 2 letters written regarding the article that Annie Janvier, Josianne Malo and I wrote about the impact of probiotics in our NICU. I just realized that Elsevier’s rules allow me under the ‘permitted scholarly posting’ … Continue reading
Probiotics prevent NEC in rats too!
Mark Underwood has been very active in the investigations of probiotics and their effects on the neonatal bowel. His new publication is a fascinating exploration of what happens in a rat model of NEC when they receive bifidobacterium infantis, also … Continue reading
Probiotics: so what about those ELBW babies?
After a comment to my previous post about probiotics, I wanted to clarify what I said about the ELBW baby, that is, the newborn with a birth weight below 1001 grams. It is true that there are few studies that … Continue reading
Neonatal Research 