Tag Archives: Probiotics

The Time for a Confirmative Necrotizing Enterocolitis Probiotics Prevention Trial in the Extremely Low Birth Weight Infant in North America Is Well Past

Posted on 23 September 2014 by Keith Barrington

What on earth are these people waiting for? A number of authors from Toronto and elsewhere have written a ridiculous editorial (entitled ‘The Time for a Confirmative Necrotizing Enterocolitis Probiotics Prevention Trial in the Extremely Low Birth Weight Infant in … Continue reading →

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Probiotics work in Germany also

Posted on 23 June 2014 by Keith Barrington

A new study from the German Neonatal Network Database compares the incidence of NEC between centers that used probiotics, centers that did not use probiotics, and centers that changed their practice part way through the data collection period from being … Continue reading →

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Probiotics in preterm infants: not just for NEC prevention any more

Posted on 20 May 2014 by Keith Barrington

A new RCT in more mature preterm infants 32 to 37 weeks compared the incidence of viral respiratory infections during the first year of life between infants who received prebiotics (galacto-oligosaccharide and polydextrose) probiotics (lactobacillus rhamnosus) or placebo between the … Continue reading →

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Probiotics: what do parents want?

Posted on 10 April 2014 by Keith Barrington

Some day, I might slow down with the probiotics posts, but not right now! A letter published in Archives reports the results of a parent survey. In the 3 NICUs implicated probiotics are given with parental information and an ‘opt-out’ … Continue reading →

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Bugs and Breast Milk

Posted on 9 April 2014 by Keith Barrington

Neonatology recently published a commentary asking the following question about routine probiotic supplementation, ‘what will it take to change practice?‘ This was immediately followed by another commentary, from Neena Modi, explaining why she is still reluctant. Although I have a … Continue reading →

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Stop the Antibiotics!

Posted on 21 February 2014 by Keith Barrington

We know that prolonged antibiotic use in preterm babies increase their chance of later developing NEC. The assumption being that the disturbance of the intestinal flora leads to the increase in susceptibility. Here is some more direct evidence to support … Continue reading →

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Yet more probiotic stuff

Posted on 14 February 2014 by Keith Barrington

Here is the other study of saccharomyces that I mentioned previously on this blog (Demirel G, Erdeve O, Celik IH, Dilmen U: Saccharomyces boulardii for prevention of necrotizing enterocolitis in preterm infants: A randomized, controlled study. Acta Paediatrica 2013) recently … Continue reading →

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Probiotics : Time for Action

Posted on 10 February 2014 by Keith Barrington

As I have noted before on this blog, our article showing the effects of the introduction of routine probiotics in our NICU has been published on-line. The Journal of Pediatrics decided to accompany it with an editorial by William Tarnow-Mordi … Continue reading →

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Cohort study of Probiotics in our NICU

Posted on 13 January 2014 by Keith Barrington

Our article describing the results of introducing routine probiotic prophylaxis in our NICU has just become available on-line. Janvier A, Malo J, Barrington KJ: Cohort Study of Probiotics in a North American Neonatal Intensive Care Unit. The Journal of pediatrics … Continue reading →

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Probiotics work, they really, really, work! (And they are safe)

Posted on 22 November 2013 by Keith Barrington

The Proprems study that I have referred to a couple of times before has now been published. This was a multicenter RCT of a probiotic preparation in 1100 very preterm infants less than 1500 grams and less than 32 weeks. … Continue reading →

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