Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Should we freeze maternal breast milk in the NICU? Pasteurize it?

Posted on 1 February 2017 by Keith Barrington

Maternal breast milk is what we should be giving to every preterm infant as much as possible. But we know that there are cases of transmission of cytomegalovirus (CMV) and reports of transmission of other pathogens to babies from breast … Continue reading →

Posted in Neonatal Research | Tagged , , , , , | 5 Comments

Neonatal Updates

Posted on 30 January 2017 by Keith Barrington

McLanders ML, et al. The cognitive aids in medicine assessment tool (CMAT) applied to five neonatal resuscitation algorithms. J Perinatol. 2016.In many delivery rooms around the world, algorithms for neonatal resuscitation steps are posted on the walls. Do they help? … Continue reading →

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Reducing antibiotic use in full term babies.

Posted on 27 January 2017 by Keith Barrington

Early onset neonatal sepsis currently has an incidence in North America among term infants of about 0.5 to 1 per thousand live births. But 15% of newborn infants have risk factors and they end up receiving antibiotics if current guidelines … Continue reading →

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How financial conflicts of interest affect medicine

Posted on 27 January 2017 by Keith Barrington

Ahn R, et al. Financial ties of principal investigators and randomized controlled trial outcomes: cross sectional study. BMJ. 2017;356. Not neonatology but a study of how principal investigators’ financial ties to the pharmaceutical industry are associated with outcomes of controlled … Continue reading →

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Happy New Review no. 2; Inhaled NO in the full term infant

Posted on 17 January 2017 by Keith Barrington

We have also updated the Cochrane review of inhaled NO in the term infant. (Barrington KJ, Finer N, Pennaforte T, Altit G. Nitric oxide for respiratory failure in infants born at or near term. Cochrane database of systematic reviews (Online). … Continue reading →

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Happy New Year! And Happy Reading; an update of the Cochrane review: nitric oxide in the preterm

Posted on 13 January 2017 by Keith Barrington

A major revision of the Cochrane review of inhaled nitric oxide gas in the preterm infant is now available. (Barrington KJ, Finer N, Pennaforte T. Inhaled nitric oxide for respiratory failure in preterm infants. Cochrane database of systematic reviews (Online). … Continue reading →

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You can’t diagnose reflux with a laryngoscope!

Posted on 23 December 2016 by Keith Barrington

I have seen in several places, and heard other neonatologists from elsewhere make comments about, a very high frequency of the diagnosis of serious reflux by ENT surgeons. Almost every time a consultation is requested, for almost any indication, the … Continue reading →

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Venous catheters and thrombosis, risk factors, consequences and treatment.

Posted on 23 December 2016 by Keith Barrington

We had a journal club for the fellows lately, everyone had to find an article about venous thrombosis and association with central catheters. We chose the topic because seem to have many more thromboses than in the past, whether that … Continue reading →

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Inhaled steroids for BPD?

Posted on 12 December 2016 by Keith Barrington

In a recent post I promoted a new Barrington rule for meta-analysis (it probably already existed somewhere but I am claiming priority anyway, it’s a “post-truth” kind of thing). The rule was that in a systematic review you shouldn’t pool … Continue reading →

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Toxicity of reflux medications in infancy

Posted on 2 December 2016 by Keith Barrington

Before I leave the topic for at least a few days, I thought I would discuss data about the toxicity of reflux medications in older children. Most of my ‘toxic placebo’ comments have been about studies in preterm infants, and … Continue reading →

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