Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Shifting the uncertainty: early head ultrasound abnormalities, and counselling parents. Part 1

Routine early head ultrasound is the de facto standard of care in preterm infants. Recent statements from learned societies usually recommend head ultrasound at around 7 days of age, and many centres do them earlier than that. Older statements suggested … Continue reading

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PAS 2023, some supplemental selected stuff

As usual, the annual meeting of PAS had too many things going on simultaneously to be able to get to all the interesting looking neonatal research. But here are a few things, that were of interest to me, and which … Continue reading

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PAS 2023, some selected stuff

Hernia repair timing One trial which will should have an impact on the care of newborn infants is the trial of early versus late hernia repair. 40 neonatal centres in the USA randomized 320 preterm infants to inguinal hernia repair … Continue reading

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I might have already mentioned this; CRPs are CRaP!

Acute phase reactants increase for many different reasons, such as being born. Other causes of increased CRP include maternal antibiotic prophylaxis, TTN, HMD, Surfactant treatment, meconium aspiration syndrome, prolonged rupture of membranes, HIE, higher birthweight, gastroschisis, and probably someone scowling … Continue reading

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An ESCape route for infants suffering opiate withdrawal

The Finnegan score was developed and evaluated in the 1970’s as the first systematic way of monitoring babies going through perinatal drug withdrawal. Although it was an advance at the time, it was not developed using modern standards, and was … Continue reading

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PAS meeting starting tomorrow. Panel Saturday afternoon!

For those of my readers going to PAS in Washington DC, I have put together a panel to discuss painful procedures in neonatal research projects, which starts at 2pm on Saturday, April 29, 2023. The stellar cast of speakers include … Continue reading

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What now for cerebral NIRS in the preterm?

Previous randomized trials of routine cerebral NIRS in preterm infants have shown that cerebral hypoxia can be reduced by responding to the signal, but in an underpowered follow up of a subgroup, there was no impact on long term outcomes. … Continue reading

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Survival after End-of-Life Discussions

Another of the articles that have been keeping me busy over the last couple of months has just been published. Boutillier B, Biran V, Janvier A, Barrington KJ. Survival and Long-term Outcomes of Children Who Survived After End-of-Life Decisions in … Continue reading

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Imaging after therapeutic hypothermia: when to do the MRI (if at all)

I had thought it was well settled that imaging soon after rewarming was as good for predicting outcomes in HIE as later imaging, but it seems that the timing, and the methodology are still uncertain. Tabacaru C, et al. Diffusion … Continue reading

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Pulmonary outcomes in the preterm: beyond BPD

A long break since my last post. I have had a couple of trips, to Arizona and to Australia, and more recently to Washington DC. With each conference I now try, if I can, to take an extra few days … Continue reading

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