Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

PAS 2023, some selected stuff

Posted on 8 May 2023 by Keith Barrington

Hernia repair timing One trial which will should have an impact on the care of newborn infants is the trial of early versus late hernia repair. 40 neonatal centres in the USA randomized 320 preterm infants to inguinal hernia repair … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments

I might have already mentioned this; CRPs are CRaP!

Posted on 5 May 2023 by Keith Barrington

Acute phase reactants increase for many different reasons, such as being born. Other causes of increased CRP include maternal antibiotic prophylaxis, TTN, HMD, Surfactant treatment, meconium aspiration syndrome, prolonged rupture of membranes, HIE, higher birthweight, gastroschisis, and probably someone scowling … Continue reading →

Posted in Neonatal Research | Tagged , | 4 Comments

An ESCape route for infants suffering opiate withdrawal

Posted on 4 May 2023 by Keith Barrington

The Finnegan score was developed and evaluated in the 1970’s as the first systematic way of monitoring babies going through perinatal drug withdrawal. Although it was an advance at the time, it was not developed using modern standards, and was … Continue reading →

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PAS meeting starting tomorrow. Panel Saturday afternoon!

Posted on 26 April 2023 by Keith Barrington

For those of my readers going to PAS in Washington DC, I have put together a panel to discuss painful procedures in neonatal research projects, which starts at 2pm on Saturday, April 29, 2023. The stellar cast of speakers include … Continue reading →

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What now for cerebral NIRS in the preterm?

Posted on 25 April 2023 by Keith Barrington

Previous randomized trials of routine cerebral NIRS in preterm infants have shown that cerebral hypoxia can be reduced by responding to the signal, but in an underpowered follow up of a subgroup, there was no impact on long term outcomes. … Continue reading →

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Survival after End-of-Life Discussions

Posted on 24 April 2023 by Keith Barrington

Another of the articles that have been keeping me busy over the last couple of months has just been published. Boutillier B, Biran V, Janvier A, Barrington KJ. Survival and Long-term Outcomes of Children Who Survived After End-of-Life Decisions in … Continue reading →

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Imaging after therapeutic hypothermia: when to do the MRI (if at all)

Posted on 19 April 2023 by Keith Barrington

I had thought it was well settled that imaging soon after rewarming was as good for predicting outcomes in HIE as later imaging, but it seems that the timing, and the methodology are still uncertain. Tabacaru C, et al. Diffusion … Continue reading →

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Pulmonary outcomes in the preterm: beyond BPD

Posted on 17 April 2023 by Keith Barrington

A long break since my last post. I have had a couple of trips, to Arizona and to Australia, and more recently to Washington DC. With each conference I now try, if I can, to take an extra few days … Continue reading →

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Development of oral feeding skills in the preterm infant

Posted on 22 February 2023 by Keith Barrington

For another project I have been involved in, I reviewed a lot of studies addressing how and when preterm babies develop their feeding skills. Which I thought I would share. Oral feeding is complicated! The first thing a baby has … Continue reading →

Posted in Neonatal Research | 3 Comments

Comment on my post about the Beneductus trial

Posted on 12 January 2023 by Keith Barrington

The authors of the Beneductus trial commented on my post about the trial, but it has somehow disappeared from the comment section of the blog, as they raise very valid points, I thought I would copy what they sent here … Continue reading →

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