Tag Archives: long term outcomes

What happened to the HeROs?

Posted on 22 September 2020 by Keith Barrington

I had to find a way of changing HeRO to Heroes as an excuse for posting a link to this video But also the results of a long term follow up of the HeRO trial have been published. The original … Continue reading →

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Does LISA protect your brain?

Posted on 17 September 2020 by Keith Barrington

A few years ago now a multicenter RCT among infants of 23 to 26 weeks gestation showed that LISA was possible in even these most immature infants., NINSAPP. Kribs A, et al. Nonintubated Surfactant Application vs Conventional Therapy in Extremely … Continue reading →

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Delayed cord clamping in the very preterm

Posted on 10 September 2020 by Keith Barrington

I haven’t written about this issue in a while, the APTS trial, and the systematic review which was published at about the same time appeared to show definitively that there was a reduction in mortality with delayed clamping compared to … Continue reading →

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ELVIS is alive!

Posted on 17 August 2020 by Keith Barrington

I was searching through the lyrics of ELVIS songs for a quote that might be more apt for this new blog post than “It’s now or ever”, which I have used previously, when I realized that I am a loser, … Continue reading →

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When should we transfuse preterm babies, and why?

Posted on 13 August 2020 by Keith Barrington

I was one of the investigators in the PINT trial (Kirpalani H, et al. The Premature Infants in Need of Transfusion (PINT) study: a randomized, controlled trial of a restrictive (low) versus liberal (high) transfusion threshold for extremely low birth … Continue reading →

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Outcomes of infants born at 22 weeks gestation; attitudes are the best predictor of survival

Posted on 10 August 2020 by Keith Barrington

Among the most immature infants, mortality and morbidity are common even if they receive active neonatal intensive care, a new systematic review has attempted to find out how common. Backes CH, et al. Proactive Neonatal Treatment at 22 Weeks of … Continue reading →

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Antenatal steroids : good, bad, or both?

Posted on 27 May 2020 by Keith Barrington

Antenatal steroids prior to very preterm birth save lives. Antenatal steroids prior to planned late preterm delivery reduce respiratory distress and increase hypoglycaemia. Might there be other long-term effects on brain structure? There are now some animal models which suggest … Continue reading →

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Linezolid seems safe for preterms, probably

Posted on 5 March 2020 by Keith Barrington

A few years ago we started having difficulty clearing Coagulase-Negative Staphylococcal (CoNS) sepsis from the blood cultures of some babies in our NICU, children with CoNS also seemed to be sicker, and to more often have thrombocytopenia. It was at … Continue reading →

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What is hypoglycaemia? Part 3. Part of the answer!

Posted on 14 February 2020 by Keith Barrington

The only way that we can find the answer to the question of what threshold blood sugar we should use to treat babies with low blood sugars is a prospective RCT, and Behold! Look! Lo! How say you? (van Kempen … Continue reading →

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What is hypoglycemia? part 2

Posted on 13 February 2020 by Keith Barrington

The new statement from the CPS, and many others, don’t discuss which measurement that we are really interested in, is it blood glucose, or plasma glucose? The different data sources are discussed as if they were all measuring the same … Continue reading →

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