Author Archives: Keith Barrington

Unknown's avatar

About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Ventilating infants with Diaphragmatic Hernia

Posted on 6 February 2016 by Keith Barrington

Snoek KG, et al. Conventional Mechanical Ventilation Versus High-frequency Oscillatory Ventilation for Congenital Diaphragmatic Hernia: A Randomized Clinical Trial (The VICI-trial). Ann Surg. 2015. There a few few remarkable things about this study; the first is part of the preamble: Since … Continue reading →

Posted in Neonatal Research | 6 Comments

A New Publication

Posted on 5 February 2016 by Keith Barrington

Janvier A, Farlow B, Barrington KJ. Cardiac surgery for children with trisomies 13 and 18: Where are we now? Seminars in Perinatology. 2016. Annie and Barb and I have just published this review of the current situation regarding cardiac surgery … Continue reading →

Posted in Neonatal Research | 2 Comments

The death knell for Xenon?

Posted on 4 February 2016 by Keith Barrington

Azzopardi D, et al. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial. The Lancet Neurology. 2016;15(2):145-53.  Babies who undergo therapeutic hypothermia for perinatal encephalopathy … Continue reading →

Posted in Neonatal Research | Tagged , | 4 Comments

Surfactant without intubation, where are we?

Posted on 4 February 2016 by Keith Barrington

A recent trial from Germany tried to answer the question of whether giving surfactant through a thin catheter while the baby was on CPAP would reduce “death or BPD” compared to intubation for surfactant. Kribs A, et al. Nonintubated Surfactant Application … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

When to deliver after Preterm Ruptured Membranes

Posted on 2 February 2016 by Keith Barrington

I have often wondered why my obstetrical colleagues would often induce labour once a woman with ruptured membranes reached 34 weeks. I wasn’t aware of any data to support doing this, or, on the other hand, any good data to … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

How frequent is Acute Kidney Injury in the NICU? Not as frequent as some publications would have you believe.

Posted on 25 January 2016 by Keith Barrington

One recent publication states that 30% of all their babies under 30 weeks gestation had Acute Kidney Injury (AKI from now on). Another from a couple of years ago reports 40% of all their babies under 1500g had AKI. Both … Continue reading →

Posted in Neonatal Research | 8 Comments

All results must be published, and all data available.

Posted on 25 January 2016 by Keith Barrington

Support for the All trials campaign has been growing, but progress seems to be slow. There are still many trials that are not published, and the impacts on science based medicine are substantial. Recently, two articles by former participants in … Continue reading →

Posted in Neonatal Research | Leave a comment

Medium Term outcomes after neonatal hypoglycemia

Posted on 22 January 2016 by Keith Barrington

A new publication from the CHYLD program that I blogged about previously: Harris DL, et al. Outcome at 2 Years after Dextrose Gel Treatment for Neonatal Hypoglycemia: Follow-Up of a Randomized Trial. The Journal of pediatrics. 2015. In this paper … Continue reading →

Posted in Neonatal Research | 1 Comment

Back to Blogging, and publishing!

Posted on 22 January 2016 by Keith Barrington

A prolonged break, which occurred for various reasons, is at an end. I have a few posts lined up for the next few days, but will start with news about a new publication, an editorial I wrote with one of … Continue reading →

Posted in Neonatal Research | 1 Comment

Proud to be a Canadian, again.

Posted on 16 December 2015 by Keith Barrington

As a lifelong socialist, I couldn’t bring myself to vote Liberal in our last election. I would have been severely tempted, but I was fortunate to live in the constituency of Tom Mulcair, my primary motivation was “anybody but Harper”. Justin … Continue reading →

Posted in Neonatal Research | 1 Comment