Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

PAS 2018: why can’t we get the Apps/website even close to being OK?

Posted on 12 May 2018 by Keith Barrington

The PAS 2018 App was an improvement over the disaster that was 2017. At least searches often worked, and you could create a schedule. But if I wanted to search for the presentations, even my own, of which I was … Continue reading →

Posted in Neonatal Research | 5 Comments

PAS 2018 No6: Brett, the HUNTER

Posted on 12 May 2018 by Keith Barrington

Brett Manley from Melbourne is now the person in the world with the greatest trial experience in the use of high flow nasal cannulae in the newborn. He has been the HIPSTER, and is now the HUNTER, I can’t find … Continue reading →

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PAS 2018 No5: the trial with no name… propranolol for early RoP, a proper trial.

Posted on 11 May 2018 by Keith Barrington

As far as I can see, this trial has no acronym, which isn’t a big deal, but it also doesn’t show up on trial registry searches, which is a big deal. Trials must be registered before starting them, it ensures … Continue reading →

Posted in Neonatal Research | Tagged , | 8 Comments

PAS 2108 No4: you little SCAMP!

Posted on 10 May 2018 by Keith Barrington

In the part of England where I was born and spent the early years of my life, and where my parents are from, the Manchester region, ‘scamp’ was a sort of affectionate term for a young child who had done … Continue reading →

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PAS 2018 No3: Should we TOLERATE the PDA?

Posted on 10 May 2018 by Keith Barrington

This was another large multicenter trial, designed to determine if routine attempts to close a moderate to large PDA at the end of the first postnatal week decreases the duration of patency, and the incidence of the combined outcome “need … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

PAS 2018 No2: let’s STOP-BPD

Posted on 10 May 2018 by Keith Barrington

The STOP-BPD trial was a multicenter trial from Holland, (registered as NTR2768) over 180 babies were randomized to each arm of this trial, they were <30 weeks or less than 1250 g at birth, and were still ventilated at 2 … Continue reading →

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PAS 2018 No1: SAIL away (and another mention by a science journalist).

Posted on 9 May 2018 by Keith Barrington

For some reason there is a small epidemic (n=2, that’s a pico-epidemic) of articles about probiotics and necrotising enterocolitis this year in the mainstream press. I was interviewed, and I am mentioned again, in this article on the NOVA “next” … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments

Important outcomes after extreme prematurity: what do parents think?

Posted on 5 May 2018 by Keith Barrington

There has been remarkably little study of the response to the question posed in the title: what do parents think is important in the outcomes of the very preterm baby? Physicians have focused on developmental progress, often as measured by … Continue reading →

Posted in Neonatal Research | Tagged | 6 Comments

Regular universal antibiotics to reduce infant mortality?

Posted on 3 May 2018 by Keith Barrington

This (Keenan JD, et al. Azithromycin to Reduce Childhood Mortality in Sub-Saharan Africa. The New England journal of medicine. 2018;378(17):1583-92 Open Access) is a new multicenter cluster randomized trial of giving all infants in a community regular azithromycin. If that … Continue reading →

Posted in Neonatal Research | Tagged , | 2 Comments

Too much oxygen is bad for adults too!

Posted on 2 May 2018 by Keith Barrington

The systematic review of the neonatal oxygen saturation targeting trials Askie LM, et al. Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants. Cochrane database of systematic reviews (Online). 2017;4:Cd011190. confirmed the increase … Continue reading →

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