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Author Archives: Keith Barrington
Hypoglycaemia, symptomatic or non-?
Many algorithms for detection and treatment of hypoglycaemia make a big deal of whether the hypoglycaemia is symptomatic or not. Symptomatic hypoglycaemia is supposed to be more dangerous in the long term, and requires more aggressive treatment. But symptoms accredited … Continue reading
Skin to skin contact reduces pain… in mothers!
Some neonatal interventions for pain relief don’t seem to work in older subjects, sucrose for example doesn’t seem effective out of the neonatal period, a study from our Emergency Room showed no benefit of sucrose for bladder catheterisation in infants … Continue reading
Should we feed insulin to preterm babies?
This was an idea I had not heard about prior to seeing this newly published trial (Mank E, et al. Efficacy and Safety of Enteral Recombinant Human Insulin in Preterm Infants: A Randomized Clinical Trial. JAMA Pediatr. 2022). The introduction … Continue reading
Posted in Neonatal Research
Tagged enteral feeding, Randomized Controlled Trials, Research Design
4 Comments
Does Gastro-Oesophageal Reflux matter in BronchoPulmonary Dysplasia?
The title is deliberately a bit vague as I wanted to discuss whether GOR contributes to the pathogenesis of BPD, and also whether it is important in infants with established BPD. Does GOR contribute to the development of BPD? There … Continue reading
What is Gastro-Oesophageal Reflux Disease (GORD, or GERD if you prefer) in the neonate?
All babies have reflux, repeated transient lower oesophageal sphincter relaxations are universal. Almost all babies have overt regurgitation, I often say that if a baby never regurgitates it may be a sign that they aren’t getting enough milk! So when … Continue reading
What do we tell families at 22 weeks?
When we counsel families about the potential outcomes for infants born profoundly preterm, I think we would all agree that we should be honest, transparent and truthful. Which includes, I would suggest, truthfulness about our own local results, as well … Continue reading
Active intensive care at 22 weeks gestation
Even the New England Journal are getting in on the act (Lee CD, et al. Neonatal Resuscitation in 22-Week Pregnancies. N Engl J Med. 2022;386(4):391-3), I guess that someone talked to the editors about the practice variation in resuscitation of … Continue reading
Speak French to your babies (or Chinese) in the NICU
This is a fascinating study from Columbus Ohio in mildly preterm babies when they reached term. (Richard C, et al. Randomized Trial to Increase Speech Sound Differentiation in Infants Born Preterm. J Pediatr. 2021) We know that prematurity and NICU … Continue reading
More musings on the microbiome
We are fortunate in neonatology to not have to worry about C difficile, partly because the name has been changed for this germ as well (now Clostridioides, rather than Clostridium), and it is one less name change to keep up … Continue reading
Survival and longer term outcomes for the extremely preterm. The NICHD network results.
In addition to the short term results that I just posted about, the publication from the NICHD NRN describes the longer term outcomes of the babies of 22 to 26 weeks GA born between 2013-2016 who completed their 2 year … Continue reading
Neonatal Research 