Tag Archives: Systematic Reviews

Clunk/click every hip

Posted on 23 October 2018 by Keith Barrington

For those of you who are not of a certain age, and brought up in England, that title will not mean very much. When seat belts in cars were first made compulsory in the UK there was a widely quoted … Continue reading →

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Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM

Posted on 20 June 2018 by Keith Barrington

The NeoProm primary publication is the result of a prolonged gestation; I remember meetings over 15 years ago when Cynthia Cole from Boston was suggesting the idea, and although she was not, I think, finally an author on any of … Continue reading →

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Too much oxygen is bad for adults too!

Posted on 2 May 2018 by Keith Barrington

The systematic review of the neonatal oxygen saturation targeting trials Askie LM, et al. Effects of targeting lower versus higher arterial oxygen saturations on death or disability in preterm infants. Cochrane database of systematic reviews (Online). 2017;4:Cd011190. confirmed the increase … Continue reading →

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The last word on delayed cord clamping in the preterm? part 3.

Posted on 10 November 2017 by Keith Barrington

Lo and behold. Fogarty M, et al. Delayed Versus Early Umbilical Cord Clamping for Preterm Infants: A Systematic Review and Meta-Analysis. Am J Obstet Gynecol. 2017. Some of the authors of the APTS trial have performed an updated systematic review, … Continue reading →

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Probiotics for extremely preterm infants

Posted on 25 May 2017 by Keith Barrington

The use of probiotics for Necrotising enterocolitis prophylaxis in the very preterm is increasing across Canada. There are apparently, though, centers that will only give them to larger preterm infants, and not to the most immature. I think that is … Continue reading →

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Fluid restriction to prevent BPD?

Posted on 14 February 2017 by Keith Barrington

In response to my previous post, one of the comments was a question about fluid volumes in the first few days of life, and whether fluid and/or sodium intake was important for the development of BPD during the early neonatal … Continue reading →

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Fluid restriction as treatment for BPD? This time with the summary of findings table.

Posted on 13 February 2017 by Keith Barrington

I realize that many of my gentle readers may not have access to the Cochrane reviews in full text as soon as they are published. The NICHD do provide free access to the neonatal reviews, (together with a useful introduction … Continue reading →

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New Publication: Does fluid restriction improve the clinical status of babies with BPD?

Posted on 10 February 2017 by Keith Barrington

I have never been convinced that fluid restriction is a good thing for kids with BPD. I think the common practice came about because of the short-term improvements in lung function that sometimes follow if you start diuretics. The idea … Continue reading →

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Should we freeze maternal breast milk in the NICU? Pasteurize it?

Posted on 1 February 2017 by Keith Barrington

Maternal breast milk is what we should be giving to every preterm infant as much as possible. But we know that there are cases of transmission of cytomegalovirus (CMV) and reports of transmission of other pathogens to babies from breast … Continue reading →

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Happy New Review no. 2; Inhaled NO in the full term infant

Posted on 17 January 2017 by Keith Barrington

We have also updated the Cochrane review of inhaled NO in the term infant. (Barrington KJ, Finer N, Pennaforte T, Altit G. Nitric oxide for respiratory failure in infants born at or near term. Cochrane database of systematic reviews (Online). … Continue reading →

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