Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

More extubation stuff

Posted on 11 October 2013 by Keith Barrington

Eduardo Banclari’s group have just published an RCT comparing success of extubation among 93 babies less than  1 kg birth weight who were put on low CPAP pressure (4 to 6) or high pressure (7 to 9 cm H2O). These were … Continue reading →

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High Flow Nasal Cannulae; finally learning about them

Posted on 11 October 2013 by Keith Barrington

The Melbourne group must get fed up of publishing important research, here is another in the PNEJM. Manley BJ, Owen LS, Doyle LW, Andersen CC, Cartwright DW, Pritchard MA, Donath SM, Davis PG: High-flow nasal cannulae in very preterm infants … Continue reading →

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Therapeutic Hypothermia: not a panacea

Posted on 11 October 2013 by Keith Barrington

If hypothermia protects the brain, maybe we should use it for anyone who is at risk of brain injury during acute illness? Fortunately other potential uses of hypothermia are being investigated, such as this:  Mourvillier B, Tubach F, van de Beek D, … Continue reading →

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Comment on my last post

Posted on 7 October 2013 by Keith Barrington

Please go see the comment from Alyssa Kent on my last post. Link is here. Alyssa is the mother of Virginia Kent, an extreme premie, and her insights are very provocative. I like the term extreme premie, makes it sound … Continue reading →

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Variation in care for extremely preterm infants

Posted on 7 October 2013 by Keith Barrington

One of the things that is striking in neonatology are the variations in outcomes of the most immature babies. In some centers, and in some countries, when a mother presents with threatened delivery at what the doctors think is 23 … Continue reading →

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The Microbiome and NecrotiSing Enterocolitis

Posted on 6 October 2013 by Keith Barrington

Fortunately Pubmed speaks both English and American, if you search on Pubmed for necrotizing enterocolitis it also gives you articles about correctly spelt gut diseases in preterm infants as well. As a North American transplant my spelling has become a … Continue reading →

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Not just a diagnosis; a baby, with a family.

Posted on 4 October 2013 by Keith Barrington

A new publication in Acta Paediatrica is written by 3 mothers (Thiele P, Berg SF, Farlow B: More than a diagnosis. Acta Paediatrica 2013 seems to be open access). All 3 of them have previously written about their experiences with … Continue reading →

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Informed consent in the NICU

Posted on 26 September 2013 by Keith Barrington

I have watched most of the presentations at the OHRP meeting, so you don’t have to. Many of the critics of SUPPORT make the same mistaken assumption, that usual care in the NICU is to individualize oxygen saturation targets, I … Continue reading →

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Prebiotics, to support growth of Probiotics, and how to kill them

Posted on 25 September 2013 by Keith Barrington

Ishizeki S, Sugita M, Takata M, Yaeshima T: Effect of administration of bifidobacteria on intestinal microbiota in low-birth-weight infants and transition of administered bifidobacteria: A comparison between one-species and three-species administration. Anaerobe 2013, 23(0):38-44. In this study the investigators report 3 … Continue reading →

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Maybe CRPs are not CRaP? Not entirely convinced yet.

Posted on 25 September 2013 by Keith Barrington

This is  a nicely done study, with interesting data, but I am not sure I agree 100% with the conclusions. Lots of newborn babies get antibiotics for suspected infection, they are usually stopped at 48 hours if the cultures are negative, … Continue reading →

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