Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

I have to change my opinion of Russell Brand

Posted on 25 October 2013 by Keith Barrington

Turns out he is bright, thoughtful, and can articulate the disillusionment of many millions. Watch his interview with Jeremy Paxman. I certainly don’t agree with everything he has to say, but his passion for the fight against economic disparity, entrenched … Continue reading →

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Neonatal Updates #39

Posted on 25 October 2013 by Keith Barrington

Storme L, Aubry E, Rakza T, Houeijeh A, Debarge V, Tourneux P, Deruelle P, Pennaforte T: Pathophysiology of persistent pulmonary hypertension of the newborn: Impact of the perinatal environment. Archives of Cardiovascular Diseases 2013, 106(3):169-177.  An excellent review article by someone … Continue reading →

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More Pain

Posted on 25 October 2013 by Keith Barrington

One comment on a previous post was about pain control for, among other things, nasogastric tube insertion. Lo and behold a new publication (Ravishankar A, Thawani R, Dewan P, Das S, Kashyap A, Batra P, Faridi MMA: Oral dextrose for … Continue reading →

Posted in Neonatal Research | Tagged , , | 4 Comments

Pain research in the newborn, what is ethical?

Posted on 21 October 2013 by Keith Barrington

Annie Janvier’s comment on my recent post made we wonder what are the ethical limits of pain research in the newborn. Let me start with an adult analogy, if a researcher wanted to investigate the efficacy of a new analgesic … Continue reading →

Posted in Neonatal Research | Tagged , , , | 3 Comments

“Saving extremely preterm babies by signing forms”

Posted on 21 October 2013 by Keith Barrington

This is great.  A journalist at the Tampa Bay Times who had an infant herself at 23 weeks gestation has just written one of the best articles about SUPPORT, from the point of view of someone who has experienced NICU from the other … Continue reading →

Posted in Neonatal Research | 2 Comments

Pain hurts

Posted on 21 October 2013 by Keith Barrington

In 2010 a paper published in the Lancet called into question the use of sucrose as an analgesic for heelsticks. (I will use the US term as I think most people understand that it refers to lancing the heel of … Continue reading →

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Do Probiotics prevent C difficile?

Posted on 18 October 2013 by Keith Barrington

My recent post about Bayesian analysis was in part prompted by this trial, just published in the Lancet, but I never got back to discussing this trial, being distracted by other things, like actual work. Nearly 3000 adults were randomized … Continue reading →

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Time is Brain

Posted on 17 October 2013 by Keith Barrington

That phrase, which has been used to denote the urgency of early stroke treatment in adults, has been purloined by Marianne Thoresen and her colleagues for their article about the importance of timely hypothermia treatment, and now by me for … Continue reading →

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Feeding during PDA treatment

Posted on 15 October 2013 by Keith Barrington

Ron Clyman and a multicenter group have just published this DAFFII trial. Which is a rather tortuous light-hearted acronym for Ductus Arteriosus Feed or Fast with Indomethcain or Ibuprofen.   (Clyman R, Wickremasinghe A, Jhaveri N, Hassinger DC, Attridge JT, Sanocka … Continue reading →

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Neonatal Updates #38

Posted on 15 October 2013 by Keith Barrington

Simons SHP, van der Lee R, Reiss IKM, van Weissenbruch MM: Clinical evaluation of propofol as sedative for endotracheal intubation in neonates. Acta Paediatrica 2013, 102(11):e487-e492 Many readers will know that I was the author of the recent CPS position statement … Continue reading →

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