Author Archives: Keith Barrington

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About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

More Pain

Posted on 25 October 2013 by Keith Barrington

One comment on a previous post was about pain control for, among other things, nasogastric tube insertion. Lo and behold a new publication (Ravishankar A, Thawani R, Dewan P, Das S, Kashyap A, Batra P, Faridi MMA: Oral dextrose for … Continue reading →

Posted in Neonatal Research | Tagged , , | 4 Comments

Pain research in the newborn, what is ethical?

Posted on 21 October 2013 by Keith Barrington

Annie Janvier’s comment on my recent post made we wonder what are the ethical limits of pain research in the newborn. Let me start with an adult analogy, if a researcher wanted to investigate the efficacy of a new analgesic … Continue reading →

Posted in Neonatal Research | Tagged , , , | 3 Comments

“Saving extremely preterm babies by signing forms”

Posted on 21 October 2013 by Keith Barrington

This is great.  A journalist at the Tampa Bay Times who had an infant herself at 23 weeks gestation has just written one of the best articles about SUPPORT, from the point of view of someone who has experienced NICU from the other … Continue reading →

Posted in Neonatal Research | 2 Comments

Pain hurts

Posted on 21 October 2013 by Keith Barrington

In 2010 a paper published in the Lancet called into question the use of sucrose as an analgesic for heelsticks. (I will use the US term as I think most people understand that it refers to lancing the heel of … Continue reading →

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Do Probiotics prevent C difficile?

Posted on 18 October 2013 by Keith Barrington

My recent post about Bayesian analysis was in part prompted by this trial, just published in the Lancet, but I never got back to discussing this trial, being distracted by other things, like actual work. Nearly 3000 adults were randomized … Continue reading →

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Time is Brain

Posted on 17 October 2013 by Keith Barrington

That phrase, which has been used to denote the urgency of early stroke treatment in adults, has been purloined by Marianne Thoresen and her colleagues for their article about the importance of timely hypothermia treatment, and now by me for … Continue reading →

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Feeding during PDA treatment

Posted on 15 October 2013 by Keith Barrington

Ron Clyman and a multicenter group have just published this DAFFII trial. Which is a rather tortuous light-hearted acronym for Ductus Arteriosus Feed or Fast with Indomethcain or Ibuprofen.   (Clyman R, Wickremasinghe A, Jhaveri N, Hassinger DC, Attridge JT, Sanocka … Continue reading →

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Neonatal Updates #38

Posted on 15 October 2013 by Keith Barrington

Simons SHP, van der Lee R, Reiss IKM, van Weissenbruch MM: Clinical evaluation of propofol as sedative for endotracheal intubation in neonates. Acta Paediatrica 2013, 102(11):e487-e492 Many readers will know that I was the author of the recent CPS position statement … Continue reading →

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More extubation stuff

Posted on 11 October 2013 by Keith Barrington

Eduardo Banclari’s group have just published an RCT comparing success of extubation among 93 babies less than  1 kg birth weight who were put on low CPAP pressure (4 to 6) or high pressure (7 to 9 cm H2O). These were … Continue reading →

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High Flow Nasal Cannulae; finally learning about them

Posted on 11 October 2013 by Keith Barrington

The Melbourne group must get fed up of publishing important research, here is another in the PNEJM. Manley BJ, Owen LS, Doyle LW, Andersen CC, Cartwright DW, Pritchard MA, Donath SM, Davis PG: High-flow nasal cannulae in very preterm infants … Continue reading →

Posted in Neonatal Research | Tagged , , , | 2 Comments