Tag Archives: Necrotising Enterocolitis

Necrotising Enterocolitis: impacts of feeding patterns

Posted on 11 October 2023 by Keith Barrington

A new review article published in J Perinatol makes many claims about feeding patterns and NEC, but I think has seriously misinterpreted the literature (Assad M, et al. Dilemmas in establishing preterm enteral feeding: where do we start and how … Continue reading →

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Probiotics. What now?

Posted on 6 October 2023 by Keith Barrington

Many of you will have seen or heard of the FDA warning about probiotics in preterm infants. In a letter (I am not in the USA, so I am not sure exactly who this letter was sent to, or the … Continue reading →

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World NEC awareness day, part 2

Posted on 17 May 2022 by Keith Barrington

As well as all the high tech mechanistic studies in NEC, such as those that I just posted about, sometimes we need to take a step back and ask some very basic questions. What is the current natural history of … Continue reading →

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World NEC awareness day.

Posted on 17 May 2022 by Keith Barrington

As we approach world NEC awareness day (May 17th) I thought I’d do a quick PubMed search to see if I’ve missed anything recently, so I started typing “necrotizing” in the search bar, which immediately suggested “necrotizing enterocolitis” as one … Continue reading →

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AAP guidance on probiotics. As wrong-headed as a head can be wrong.

Posted on 9 May 2022 by Keith Barrington

The AAP issued guidance on probiotic use in the preterm infant last year in the form of what they call a “clinical report”, which I didn’t comment on at the time, I thought it might be a bit redundant as … Continue reading →

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Survival and outcomes for the extremely preterm. The NICHD network results continue to improve: Can we do even better?

Posted on 20 January 2022 by Keith Barrington

A new publication from the NRN describes short term outcomes and care practices of babies from 22 to 28 weeks gestation born in recent years (2013 to 2018) and for those born in 2013-2016 results of evaluations of those followed … Continue reading →

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Probiotics in preterms; what’s new? Part 2

Posted on 19 January 2022 by Keith Barrington

Rao S, et al. Probiotic supplementation in neonates with congenital gastrointestinal surgical conditions: a pilot randomised controlled trial. Pediatr Res. 2022. When we started using probiotics there had been a couple of case reports of probiotic associated sepsis in infants … Continue reading →

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Probiotics in preterms; what’s new? Part 1

Posted on 18 January 2022 by Keith Barrington

I haven’t, surprisingly, posted about probiotics recently, but there are some new findings in the literature that warrant discussion. Granger C, et al. Necrotising enterocolitis, late-onset sepsis and mortality after routine probiotic introduction in the UK. Arch Dis Child Fetal … Continue reading →

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Intestinal perforation in the very preterm, what causes it, and what to do about it.

Posted on 24 September 2021 by Keith Barrington

There are 2 main causes of intestinal perforation in the very preterm, Necrotising Enterocolitis and Spontaneous Perforation. NEC, as I have previously discussed, may be a convenient name for a few different conditions which present in a similar fashion. In … Continue reading →

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Opioid infusions for ventilated preterm babies

Posted on 13 September 2021 by Keith Barrington

Many practices in neonatology are variable between NICUs, and many vary from year to year; without any good scientific data practices become fashionable or routine or ingrained without necessarily having an evidence base to support them. One such practice is … Continue reading →

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