Tag Archives: Analgesia

Drug approval in neonates; what to do? and what is this dexmedetty stuff?

Posted on 29 January 2014 by Keith Barrington

Most of the drugs that we routinely use in neonatology do not have a specific license for neonatal use. This is true I think in every jurisdiction around the world, the USA, Canada, Australia, and Europe, but I don’t know … Continue reading →

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Preterm twins seem to care for one another

Posted on 14 January 2014 by Keith Barrington

There has been a lot of talk about co-bedding twins in the NICU, but relatively little research. I was involved in an RCT of co-bedding in preterm twins, looking at responses to painful stimuli (67 pars of twins were recruited). … Continue reading →

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More Pain

Posted on 25 October 2013 by Keith Barrington

One comment on a previous post was about pain control for, among other things, nasogastric tube insertion. Lo and behold a new publication (Ravishankar A, Thawani R, Dewan P, Das S, Kashyap A, Batra P, Faridi MMA: Oral dextrose for … Continue reading →

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Pain research in the newborn, what is ethical?

Posted on 21 October 2013 by Keith Barrington

Annie Janvier’s comment on my recent post made we wonder what are the ethical limits of pain research in the newborn. Let me start with an adult analogy, if a researcher wanted to investigate the efficacy of a new analgesic … Continue reading →

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Pain hurts

Posted on 21 October 2013 by Keith Barrington

In 2010 a paper published in the Lancet called into question the use of sucrose as an analgesic for heelsticks. (I will use the US term as I think most people understand that it refers to lancing the heel of … Continue reading →

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Premedication for Intubation

Posted on 13 November 2012 by Keith Barrington

There are several studies of what premedication should be used for intubation of the newborn. An analgesic or anesthetic agent should be given in to reduce pain, which also reduces the adverse physiologic consequences of the intubation. Several studies of … Continue reading →

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Opioids and Cerebral Development in the Newborn

Posted on 31 October 2012 by Keith Barrington

An extremely interesting “ratling” study from the latest “Neonatology” (Dührsen L, Simons SHP, Dzietko M, Genz K, Bendix I, Boos V, Sifringer M, Tibboel D, Felderhoff-Mueser U: Effects of repetitive exposure to pain and morphine treatment on the neonatal rat … Continue reading →

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Analgesia and co-bedding or kangaroo care

Posted on 11 September 2012 by Keith Barrington

Campbell-Yeo ML, Johnston CC, Joseph KS, Feeley N, Chambers CT, Barrington KJ: Cobedding and Recovery Time After Heel Lance in Preterm Twins: Results of a Randomized Trial. Pediatrics 2012. If I might be permitted a little self-promotion… this new study … Continue reading →

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Weekly Updates #3

Posted on 8 August 2012 by Keith Barrington

A few new publications (I know it’s not quite weekly, but I am on vacation!): Nguyen TP, Amon E, Al-Hosni M, Gavard JA, Gross G, Myles TD: “Early” versus “late” 23-week infant outcomes. Am J Obstet Gynecol 2012(0). Not too … Continue reading →

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Pain relief for intramuscular injections

Posted on 10 May 2012 by Keith Barrington

Sometimes we can’t avoid giving an IM injection, even though they are painful. Some vaccines should be given IM, and the routine needle in the thigh of every baby for vitamin K is a rite of passage, that has become standard everywhere. … Continue reading →

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