Author Archives: Keith Barrington

Unknown's avatar

About Keith Barrington

I am a neonatologist and clinical researcher at Sainte Justine University Health Center in Montréal

Neonatal Updates

Posted on 22 May 2014 by Keith Barrington

Dardas M, Gill SR, Grier A, Pryhuber GS, Gill AL, Lee Y-H, et al. The Impact of Postnatal Antibiotics on the Preterm Intestinal Microbiome. Pediatr Res. 2014. It will be no surprise to readers of this blog that antibiotics are … Continue reading →

Posted in Neonatal Research | Leave a comment

All trials reported, all results available

Posted on 20 May 2014 by Keith Barrington

The ‘All trials’ campaign is picking up steam, a new video is embedded below. I think the inclusion of a patient volunteer was a great idea, the altruistic aspect of consent for clinical trials, and the betrayal of that altruism … Continue reading →

Posted in Neonatal Research | Leave a comment

Probiotics in preterm infants: not just for NEC prevention any more

Posted on 20 May 2014 by Keith Barrington

A new RCT in more mature preterm infants 32 to 37 weeks compared the incidence of viral respiratory infections during the first year of life between infants who received prebiotics (galacto-oligosaccharide and polydextrose) probiotics (lactobacillus rhamnosus) or placebo between the … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment

Hero: Not just for infections any more

Posted on 15 May 2014 by Keith Barrington

Sullivan BA, Grice SM, Lake DE, Moorman JR, Fairchild KD. Infection and Other Clinical Correlates of Abnormal Heart Rate Characteristics in Preterm Infants. The Journal of pediatrics. 2014. Monitoring for abnormal heart rate characteristics has previously been shown in a … Continue reading →

Posted in Neonatal Research | Tagged , | Leave a comment

Poietins for the brain?

Posted on 14 May 2014 by Keith Barrington

Ohls RK, Kamath-Rayne BD, Christensen RD, Wiedmeier SE, Rosenberg A, Fuller J, et al. Cognitive Outcomes of Preterm Infants Randomized to Darbepoetin, Erythropoietin, or Placebo. Pediatrics. 2014. I’ve written about this trial before, a smallish 3 arm trial of erythropoietin, … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Funny shaped heads? You can take the helmet off now.

Posted on 13 May 2014 by Keith Barrington

I often see kids around my hospital wearing orthotic helmets, designed to make their heads more round (some of them ex-preterms), and I often wondered if they really work. A new RCT from the Netherlands shows no effect . Renske MvW, Leo … Continue reading →

Posted in Neonatal Research | Tagged | Leave a comment

Neonatal Updates

Posted on 12 May 2014 by Keith Barrington

Lipstein EA, Dodds CM, Britto MT. Real Life Clinic Visits Do Not Match the Ideals of Shared Decision Making. The Journal of pediatrics. 2014. The investigators video-taped discussion of higher risk interventions for chronic conditions (juvenile rheumatoid arthritis and inflammatory bowel … Continue reading →

Posted in Neonatal Research | Leave a comment

Prophylactic fluconazole works; but we shouldn’t use it?

Posted on 6 May 2014 by Keith Barrington

A new high quality multicenter RCT examined the effects of fluconazole prophylaxis in about 360 very tiny babies (VTB), that is they weighed less than 750g at birth. They were enrolled in the first 5 days of life to fluconazole … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

High Frequency Ventilation and long term pulmonary outcomes

Posted on 6 May 2014 by Keith Barrington

The UK Oscillation study (UKOS) was a large multicenter trial in the UK of high-frequency compared to conventional ventilation; 800 babies <29 weeks gestation were randomized, if they were intubated from birth and were less than 1 hour old, to … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Annual PAS meeting

Posted on 6 May 2014 by Keith Barrington

Just home after an extremely busy, as usual, PAS meeting In Vancouver. Please sir, can I be excused, my brain is full. I will blog a bit about it in the next few days, in the mean time, I will … Continue reading →

Posted in Neonatal Research | Leave a comment