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Author Archives: Keith Barrington
The Eyes have it! Retinopathy of Prematurity updates
A review article in the PNEJM introducing the basic concepts in the pathophysiology and treatment of retinopathy of prematurity (Hartnett ME, Penn JS: Mechanisms and management of retinopathy of prematurity. Prestigious New England Journal of Medicine 2012, 367(26):2515-2526). I think … Continue reading
Assisted Reproductive Technologies, and how they affect babies.
ARTs of course affect babies, because they produce babies. Recent advances in ART, however, have not taken much notice of babies. Many changes in technique have been introduced without any investigation of the effects on the final product. If I … Continue reading
Not neonatology: let it snow, let it snow, let it snow!
I hope all my loyal fans (!) are not too disappointed by the lack of posts over the past few days, it was Newtonmas after all. Also, a couple of days after the celebration of the great man’s birthday, there … Continue reading
Posted in Neonatal Research
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Gastro-esophageal Reflux, are we thick enough?
Making the milk thicker, in order to make it harder to reflux, has a long history in the treatment of GE reflux, or spitting-up babies. As I mentioned in a previous post there are some thickeners that have been associated … Continue reading
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Probiotics: more than enough!
Yet another small RCT of probiotics. This time 150 infants less than 1500 grams birth weight in an NICU in Mexico were randomized to a mixture of 4 different Lactobacilli and Bifidobacterium infantis or control. There was a reduction in … Continue reading
Posted in Neonatal Research
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Reducing Global Neonatal Mortality
Melinda Gates has written a column in the Economist where she notes that the improvements in child and maternal mortality seen in response to the millennium development goals have not been reflected in reductions in neonatal mortality. The column is short, … Continue reading
Weekly Updates #18
Abbas W, Attia NI, Hassanein SM: Two-stage single-volume exchange transfusion in severe hemolytic disease of the newborn. The journal of maternal-fetal & neonatal medicine. 2012, 25(7):1080-1083. In this randomized clinical trial the authors did 104 exchange transfusions, they randomized the … Continue reading
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Is the glass 81% full or 19% empty?
The new Epicure 2 data show encouraging trends in outcomes in the UK and Ireland for extremely preterm babies. Survival rates have improved significantly over the whole of the British Isles, Here for example is one of the figures from … Continue reading
I am Epicurious…
Two publications have just appeared from the EPICURE 2 study. The first (Costeloe KL, Hennessy EM, Haider S, Stacey F, Marlow N, Draper ES: Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 … Continue reading
Weekly Updates #17
Moon C, Lagercrantz H, Kuhl PK: Language experienced in utero affects vowel perception after birth: A two-country study. Acta Paediatrica 2012. This is neat, the researchers played recordings of different vowel sounds to Swedish and American babies who were just … Continue reading
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Neonatal Research 