Monthly Archives: February 2016

Enhanced Nutrition

Posted on 9 February 2016 by keithbarrington

Strømmen K, et al. Enhanced Nutrient Supply to Very Low Birth Weight Infants is Associated with Improved White Matter Maturation and Head Growth. Neonatology. 2015;107(1):68-75. This is a report of a secondary outcome of a small RCT, there were only … Continue reading →

Posted in Neonatal Research | Tagged , , | Leave a comment

Neonatal Updates

Posted on 9 February 2016 by keithbarrington

Glasson EJ, et al. Improved Survival in Down Syndrome over the Last 60 Years and the Impact of Perinatal Factors in Recent Decades. The Journal of pediatrics. 2016;169:214-20.e1. This is a fascinating study, showing dramatic improvements in the survival of persons … Continue reading →

Posted in Neonatal Research | 1 Comment

Interesting comments

Posted on 9 February 2016 by keithbarrington

I get a small number of comments on the blog, almost always interesting, depending on how you view the content you may not have noticed them. Three of my recent posts have stimulated some comments that are worthwhile: If you … Continue reading →

Posted in Neonatal Research | Leave a comment

Ventilating infants with Diaphragmatic Hernia

Posted on 6 February 2016 by keithbarrington

Snoek KG, et al. Conventional Mechanical Ventilation Versus High-frequency Oscillatory Ventilation for Congenital Diaphragmatic Hernia: A Randomized Clinical Trial (The VICI-trial). Ann Surg. 2015. There a few few remarkable things about this study; the first is part of the preamble: Since … Continue reading →

Posted in Neonatal Research | 6 Comments

A New Publication

Posted on 5 February 2016 by keithbarrington

Janvier A, Farlow B, Barrington KJ. Cardiac surgery for children with trisomies 13 and 18: Where are we now? Seminars in Perinatology. 2016. Annie and Barb and I have just published this review of the current situation regarding cardiac surgery … Continue reading →

Posted in Neonatal Research | 2 Comments

The death knell for Xenon?

Posted on 4 February 2016 by keithbarrington

Azzopardi D, et al. Moderate hypothermia within 6 h of birth plus inhaled xenon versus moderate hypothermia alone after birth asphyxia (TOBY-Xe): a proof-of-concept, open-label, randomised controlled trial. The Lancet Neurology. 2016;15(2):145-53.  Babies who undergo therapeutic hypothermia for perinatal encephalopathy … Continue reading →

Posted in Neonatal Research | Tagged , | 4 Comments

Surfactant without intubation, where are we?

Posted on 4 February 2016 by keithbarrington

A recent trial from Germany tried to answer the question of whether giving surfactant through a thin catheter while the baby was on CPAP would reduce “death or BPD” compared to intubation for surfactant. Kribs A, et al. Nonintubated Surfactant Application … Continue reading →

Posted in Neonatal Research | Tagged , , , | 1 Comment

When to deliver after Preterm Ruptured Membranes

Posted on 2 February 2016 by keithbarrington

I have often wondered why my obstetrical colleagues would often induce labour once a woman with ruptured membranes reached 34 weeks. I wasn’t aware of any data to support doing this, or, on the other hand, any good data to … Continue reading →

Posted in Neonatal Research | Tagged , , | 2 Comments